Metformin Hydrochloride Extended-Release Tablets

DRUG4 trials

Sponsors

UConn Health, Johns Hopkins University, Shandong Suncadia Medicine Co., Ltd., Brigham and Women's Hospital

Conditions

Age-Related ImmunodeficiencyAgingAsthmaAsthma ChronicDiabetesOverweight and ObesityPrimary Sclerosing Cholangitis (PSC)Vaccine Response Impaired

Phase 1

Vaccination Efficacy With Metformin in Older Adults

CompletedNCT03996538

UConn HealthAge-Related Immunodeficiency, Aging, Vaccine Response Impaired

Start: 2019-06-05End: 2020-02-04Updated: 2020-07-23

Study on Drug Interaction of Metformin Tablets and HRS-7535 Tablets in Healthy Human

CompletedNCT06727838

Shandong Suncadia Medicine Co., Ltd.Diabetes

Start: 2024-12-31End: 2025-01-25Updated: 2026-04-24

Phase 2

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

RecruitingNCT06273072

Johns Hopkins UniversityAsthma, Asthma Chronic, Overweight and Obesity

Start: 2024-12-09End: 2028-12-31Target: 100Updated: 2026-10-16

FEAST and HOPE: Redox PSC Pilot Study

Not yet recruitingNCT07898839

Brigham and Women's HospitalPrimary Sclerosing Cholangitis (PSC)

Start: 2027-01-01End: 2029-06-01Target: 15Updated: 2026-10-27