Metformin Hydrochloride ER

DRUG2 trials

Sponsors

Brian Zuckerbraun, Wake Forest University Health Sciences

Conditions

Inflammatory ResponseSarcoma MetastaticSarcoma, Soft Tissue

Phase 1

Effects of Metformin in a Non-Diabetic Patient Population

CompletedNCT03772964

Brian ZuckerbraunInflammatory Response

Start: 2019-01-22End: 2020-03-31Updated: 2023-01-11

Phase 2

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

RecruitingNCT07291297

Wake Forest University Health SciencesSarcoma Metastatic, Sarcoma, Soft Tissue

Start: 2026-03-04End: 2033-10-01Target: 50Updated: 2026-07-23