Metformin ER

DRUG10 trials

Sponsors

Laboratorios Silanes S.A. de C.V., Massachusetts General Hospital, M.D. Anderson Cancer Center, Boehringer Ingelheim, Matthew Neal MD

Conditions

AgingColorectal CarcinomaColorectumHealthyIntermittent ClaudicationPolycystic Ovary SyndromePreeclampsia

Phase 1

Tolerability and Pharmacokinetics of Metformin and Metformin Extended Release (ER)

CompletedNCT00941239

Laboratorios Silanes S.A. de C.V.Healthy

Start: 2007-01-31End: 2007-02-28Updated: 2018-01-30

An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin

TerminatedNCT01816659

M.D. Anderson Cancer CenterColorectal Carcinoma

Start: 2013-05-31End: 2014-08-31Updated: 2015-11-18

Bioequivalence of a FDC Tablet of Linagliptin/Metformin (5mg/1000mg) Extended Release in Healthy Subjects

CompletedNCT02084082

Boehringer IngelheimHealthy

Start: 2014-04-30End: 2014-07-31Updated: 2016-08-04

Bioequivalence of a FDC Tablet of Linagliptin/Metformin (2.5mg/750mg) Extended Release in Healthy Subjects

CompletedNCT02121509

Boehringer IngelheimHealthy

Start: 2014-05-31End: 2014-07-31Updated: 2016-08-04

Phase 3

REMAP Trial for Optimizing Surgical Outcomes at UPMC

TerminatedNCT03861767

Matthew Neal MDAging

Start: 2019-04-15End: 2022-09-23Updated: 2024-06-18

MetfOrmin BenefIts Lower Extremities With Intermittent Claudication

RecruitingNCT05132439

VA Office of Research and DevelopmentIntermittent Claudication

Start: 2022-03-01End: 2032-02-28Target: 200Updated: 2026-04-21

PI4 - A Trial Assessing Metformin to Prolong Gestation in Preterm Preeclampsia

RecruitingNCT06033131

Lina BergmanPreeclampsia

Start: 2024-01-19End: 2029-12-31Target: 294Updated: 2026-08-07

Unknown Phase

Polycystic Ovary Syndrome Genetics and Treatment Response

Massachusetts General HospitalPolycystic Ovary Syndrome

Start: 2011-06-30End: 2019-10-31Target: 200Updated: 2018-08-16

Prospective Trial of Metformin - Chemoprevention Role

WithdrawnNCT01550900

M.D. Anderson Cancer CenterColorectum

Start: 2013-07-31Updated: 2013-04-05

Metformin Treatment in Polycystic Ovary Syndrome (PCOS)

Massachusetts General HospitalPolycystic Ovary Syndrome

Start: 2014-07-31End: 2020-12-31Target: 20Updated: 2018-08-16

Related Papers

Does metformin prolong pregnancy in preterm pre-eclampsia? A study protocol for a South African, hospital-based double-blind, randomised, placebo-controlled trial

BMJ Open2024-06-018 citations

The Impact of COVID-19 Research on the Development of Scalable Frameworks for Efficient Clinical Trials in Cardiovascular Medicine

Canadian Journal of Cardiology2023-03-153 citations

MetfOrmin BenefIts Lower Extremities with Intermittent Claudication (MOBILE IC): randomized clinical trial protocol.

2023-01-216 citations

Implementation of the Randomized Embedded Multifactorial Adaptive Platform for COVID-19 (REMAP-COVID) trial in a US health system-lessons learned and recommendations.

2021-01-2836 citations

Strategies to Promote ResiliencY (SPRY): a randomised embedded multifactorial adaptative platform (REMAP) clinical trial protocol to study interventions to improve recovery after surgery in high-risk patients

BMJ Open2020-09-0117 citations