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Metfomin

DRUG5 trials

Sponsors

University of Texas Southwestern Medical Center, Cairo University, Erbil Polytechnic University, Uruk University, Fudan University

Conditions

Breast CancerElderlyEndometrial Hyperplasia and Endometrial CancersMild Cognitive ImpairmentObese DiabeticsObese Patients (BMI ≥ 30 kg/m²)Overweight or ObesityPolycystic Ovary Syndrome

Phase 1

The Efficacy and Safety of Metformin Intervention in Elderly Overweight or Obesity With Mild Cognitive Impairment
RecruitingNCT07395960
Fudan UniversityElderly, Mild Cognitive Impairment, Overweight or Obesity
Start: 2025-09-01End: 2026-09-30Target: 54Updated: 2026-02-09

Phase 3

The Combined Effect of N-Acetyl Cysteine and Metformin in Polycystic Ovary Syndrome Patients
RecruitingNCT06836128
Cairo UniversityPolycystic Ovary Syndrome
Start: 2025-03-01End: 2026-05-01Target: 102Updated: 2025-07-09

Phase 4

The Role of CYP8B1 Polymorphisms in Modulating the Biochemical Pathways Affected by SGLT2 Inhibitors in T2DM and Obesity
CompletedNCT07120828
Erbil Polytechnic UniversityObese Diabetics, Obese Patients (BMI ≥ 30 kg/m²), Type 2 Diabetes
Start: 2025-07-15End: 2026-03-15Updated: 2026-03-17

Unknown Phase

Preservation of Beta-cell Function in Type 2 Diabetes Mellitus
CompletedNCT00232583
University of Texas Southwestern Medical CenterType 2 Diabetes Mellitus
Start: 2003-11-30End: 2011-12-31Updated: 2017-12-14
Effect of Metformin on Endometrial Thickness in Postmenopausal Breast Cancer Patients Receiving Tamoxifen
CompletedNCT07145827
Uruk UniversityBreast Cancer, Endometrial Hyperplasia and Endometrial Cancers
Start: 2024-01-02End: 2025-07-01Updated: 2025-09-12