Metaclopramide

DRUG4 trials

Sponsors

The University of Texas Health Science Center, Houston, Franklyn Cladis, Institute of Liver and Biliary Sciences, India, Millennium Pharmaceuticals, Inc.

Conditions

CirrhosisDiabetes Mellitus and Gastroparesis, Idiopathic GastroparesisGastroesophageal RefluxPost Operative Nausea and VomitingRescue Emetic Therapy

Phase 2

A Study to Evaluate the Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) for TAK-906 in Participants With Diabetes Mellitus and Gastroparesis (DG) or With Idiopathic Gastroparesis (IG)

CompletedNCT03268941

Millennium Pharmaceuticals, Inc.Diabetes Mellitus and Gastroparesis, Idiopathic Gastroparesis

Start: 2017-09-26End: 2018-03-09Updated: 2021-01-06

Phase 3

Medical Treatment for Gastroesophageal Reflux Disease (GERD) in Preterm Infants

CompletedNCT00131248

The University of Texas Health Science Center, HoustonGastroesophageal Reflux

Start: 2004-04-30End: 2008-03-31Updated: 2014-01-15

Unknown Phase

Rescue Emetic Therapy for Children Having Elective Surgery

WithdrawnNCT01067677

Franklyn CladisPost Operative Nausea and Vomiting, Rescue Emetic Therapy

Start: 2010-02-28End: 2014-02-28Updated: 2017-11-14

To Determine the Role of Prokinetics in Feed Intolerance in Critically Ill Cirrhosis

CompletedNCT02528760

Institute of Liver and Biliary Sciences, IndiaCirrhosis

Start: 2015-09-24End: 2017-08-31Updated: 2017-11-21

Related Papers

The pharmacokinetics of oral trazpiroben (<scp>TAK</scp>‐906) after organic anion transporting polypeptide <scp>1B1</scp>/<scp>1B3</scp> inhibition: A phase I, randomized study

Clinical and Translational Science2022-04-236 citations

Evaluation of the pharmacokinetics of trazpiroben (TAK‐906) in the presence and absence of the proton pump inhibitor esomeprazole

Clinical and Translational Science2022-02-262 citations

Evaluating the Safety, Tolerability, and Disposition of Trazpiroben, a D<sub>2</sub>/D<sub>3</sub> Receptor Antagonist: Phase I Single‐ and Multiple‐Ascending Dose Studies in Healthy Japanese Participants

Clinical Pharmacology in Drug Development2021-12-291 citations

Randomised clinical trial: safety, pharmacokinetics and pharmacodynamics of trazpiroben (TAK‐906), a dopamine D<sub>2</sub>/D<sub>3</sub> receptor antagonist, in patients with gastroparesis

Alimentary Pharmacology & Therapeutics2021-06-2024 citations