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Mesenchymal Stem Cells (MSCs)

BIOLOGICAL12 trials

Sponsors

CHRU De Nancy, Hospital San Carlos, Madrid, M.D. Anderson Cancer Center, Medical University of South Carolina, The Cleveland Clinic

Conditions

Adult Respiratory Distress SyndromeAnal FistulaBlood And Marrow TransplantationCOVID-19 PneumoniaChronic DiseaseChronic Radiation ProctitisComplex Perianal FistulasCrohn's Disease

Phase 1

Mesenchymal Stem Cells (MSCs) for Treatment of Acute Respiratory Distress Syndrome (ARD) in Patients With Malignancies
CompletedNCT02804945
M.D. Anderson Cancer CenterAdult Respiratory Distress Syndrome, Blood And Marrow Transplantation
Start: 2017-02-24End: 2019-06-13Updated: 2020-04-10
Cellular Therapy for Type 1 Diabetes Using Mesenchymal Stem Cells
Active, not recruitingNCT04061746
Medical University of South CarolinaDiabetes Mellitus, Type 1
Start: 2020-02-27End: 2027-05-30Target: 60Updated: 2026-04-22
Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in Crohn's
WithdrawnNCT04073472
The Cleveland ClinicAnal Fistula, Crohn's Disease, Fistula +2
Start: 2021-06-01End: 2023-06-01Updated: 2026-04-15
Mesenchymal Stem Cells for Age-Related Frailty
WithdrawnNCT05284604
VA Office of Research and DevelopmentFrailty
Start: 2023-01-31End: 2023-01-31Updated: 2023-02-06
Stem Cells for the Treatment of Pouchitis
WithdrawnNCT05578508
The Cleveland ClinicCrohn's Disease, Inflammatory Bowel Diseases, Pouch, Ileal +2
Start: 2022-04-01End: 2024-02-01Updated: 2026-04-16
Evaluate the Distribution and Dynamic Behavior of TH-SC01 Cells in Vivo in Patients With Perianal Fistula
RecruitingNCT06429241
Jiangsu Topcel-KH Pharmaceutical Co., Ltd.Anal Fistula, Complex Perianal Fistulas, Crohn's Disease
Start: 2024-04-08End: 2025-12-31Target: 8Updated: 2024-06-12
Umbilical-Cord-Derived Mesenchymal Stem Cells Injection for Chronic Radiation Proctitis
RecruitingNCT06438809
Jiangsu Topcel-KH Pharmaceutical Co., Ltd.Chronic Radiation Proctitis
Start: 2024-05-24End: 2025-05-31Target: 24Updated: 2024-06-21
Evaluate the Distribution and Dynamic Behavior of Nuclide Labeled TH-SC01 Cells in Vivo in Patients With Radiation Proctitis
Not yet recruitingNCT06925607
Jiangsu Topcel-KH Pharmaceutical Co., Ltd.Radiation Proctitis
Start: 2025-04-30End: 2026-12-31Target: 6Updated: 2025-04-13

Phase 2

Mensenchymal Stem Cell (MSC) Included in OrthADAPT Membrane for Rotator Cuff Tears Repair
NCT01687777
Hospital San Carlos, MadridChronic Disease
Start: 2010-05-31End: 2013-12-31Target: 10Updated: 2012-09-19
Treatment of Severe COVID-19 Pneumonia With Allogeneic Mesenchymal Stem Cells
CompletedNCT04361942
Red de Terapia CelularCOVID-19 Pneumonia
Start: 2020-05-01End: 2021-10-28Updated: 2024-02-02
Effects of mesenchymal stem cells administration on organ failure during septic shock: Phase II randomized comprator-controlled study CHOC-MSC
RecruitingCTIS2024-518019-20-00
CHRU De NancyLa population concernée est celle des patients hospitalisés en réanimation présentant un choc septique d’origine communautaire très sévère (≥ 2 défaillances d’organes autres qu’hémodynamiques) depuis moins de 12 heures.
Start: 2021-10-19Target: 66Updated: 2025-06-23

Phase 4

Treatment of Oral Chronic Graft-versus-host Disease With Human Umbilical Cord Mesenchymal Stem Cell Dressing
NCT06149832
Southwest Hospital, ChinaMesenchymal Stem Cells
Start: 2023-11-30End: 2023-11-30Target: 38Updated: 2023-11-29

Related Papers

858-P: Recruitment Strategies for a Cellular Therapy Study for Type 1 Diabetes
Diabetes2023-06-20