Mesenchymal Stem Cells (MSC)

BIOLOGICAL6 trials

Sponsors

University of Liege, The University of Texas Health Science Center, Houston, Red de Terapia Celular, Hadassah Medical Organization, Cellcolabs Clinical SPV Limited

Conditions

Amyotrophic Lateral SclerosisCrohn's DiseaseIschemic CardiomyopathyKnee Arthritis OsteoarthritisLupus ErythematosusLupus NephritisMultiple Sclerosis

Phase 1

Mesenchymal Stem Cell Therapy for the Treatment of Severe or Refractory Inflammatory and/or Autoimmune Disorders

TerminatedNCT01540292

University of LiegeCrohn's Disease

Start: 2013-02-01End: 2015-12-31Updated: 2021-05-12

Repeated Mesenchymal Stem Cell Injections in ALS

CompletedNCT04821479

Hadassah Medical OrganizationAmyotrophic Lateral Sclerosis

Start: 2016-01-01End: 2020-12-31Updated: 2021-03-29

Effects of Repeated Mesenchymal Stem Cells (MSC) in Patients With Progressive Multiple Sclerosis

CompletedNCT04823000

Hadassah Medical OrganizationMultiple Sclerosis

Start: 2013-01-01End: 2020-04-01Updated: 2021-03-30

Phase 2

Combination of Mesenchymal and C-kit+ Cardiac Stem Cells as Regenerative Therapy for Heart Failure

CompletedNCT02501811

The University of Texas Health Science Center, HoustonIschemic Cardiomyopathy

Start: 2015-10-31End: 2020-07-22Updated: 2021-04-26

Treatment of Lupus Nephritis With Allogeneic Mesenchymal Stem Cells

RecruitingNCT03673748

Red de Terapia CelularLupus Erythematosus, Lupus Nephritis

Start: 2022-12-27End: 2028-12-01Target: 20Updated: 2026-08-18

An Open-Label, Double-Treatment Group Study to Evaluate the Efficacy and Safety of Human Allogeneic Bone-Marrow- Derived Mesenchymal Stromal Cell Product StromaForte Compared With Hyaluronic Acid for the Treatment of Knee Osteoarthritis

RecruitingNCT07542808

Cellcolabs Clinical SPV LimitedKnee Arthritis Osteoarthritis

Start: 2026-04-27End: 2027-09-27Target: 140Updated: 2026-04-21

Related Papers

Changes in Circulating Biomarkers in Patients With Ischemic Heart Failure After Treatment With Autologous Mesenchymal Stromal Cells and c-Kit-Positive Cardiac Cells, Alone or in Combination: Results From the Cardiovascular Cell Therapy Research Network CONCERT-HF Clinical Trial.

2026-04-20

Extracellular volume-guided late gadolinium enhancement analysis for non-ischemic cardiomyopathy: The Women’s Interagency HIV Study

BMC Medical Imaging2021-07-272 citations

Long-Term Clinical and Immunological Effects of Repeated Mesenchymal Stem Cell Injections in Patients With Progressive Forms of Multiple Sclerosis

Frontiers in Neurology2021-05-3139 citations

Abstract 14080: A Phase II Randomized, Double-blind, Controlled Trial of Combined Mesenchymal Stromal Cells and C-kit+ Cardiac Progenitor Cells in Ischemic Heart Failure: The CCTRN CONCERT-HF Trial

Circulation2020-11-121 citations

Dose-dependent improvement of cardiac function in a swine model of acute myocardial infarction after intracoronary administration of allogeneic heart-derived cells.

2019-05-3131 citations

Rationale and Design of the CONCERT-HF Trial (Combination of Mesenchymal and c-kit <sup>+</sup> Cardiac Stem Cells As Regenerative Therapy for Heart Failure)

Circulation Research2018-04-27100 citations