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Mercaptopurine Oral Suspension

DRUG2 trials

Sponsors

National Cancer Institute (NCI), Children's Oncology Group

Conditions

B Acute Lymphoblastic LeukemiaB Lymphoblastic LymphomaDown SyndromeStage II T Lymphoblastic Leukemia/LymphomaStage III T Lymphoblastic Leukemia/LymphomaStage IV T Lymphoblastic Leukemia/LymphomaT Acute Lymphoblastic LeukemiaT Lymphoblastic Lymphoma

Phase 2

Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL)
Not yet recruitingNCT07072585
Children's Oncology GroupStage III T Lymphoblastic Leukemia/Lymphoma, Stage II T Lymphoblastic Leukemia/Lymphoma, Stage IV T Lymphoblastic Leukemia/Lymphoma +2
Start: 2026-06-28End: 2035-09-01Target: 1708Updated: 2025-12-31

Phase 3

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia
Active, not recruitingNCT03914625
National Cancer Institute (NCI)B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma, Down Syndrome
Start: 2019-07-03End: 2027-09-30Target: 6720Updated: 2026-04-03

Related Papers

Inadequate social support and household material hardship among children with pediatric acute lymphoblastic leukemia: A report from the Children's oncology group Trial AALL1731
Blood2025-11-03
Feasibility of collecting social determinants of health data in the frontline pediatric acute lymphoblastic leukemia (ALL) trial AALL1731: A report from the Children's oncology group
Blood2025-11-03
Blinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children
New England Journal of Medicine2024-12-07122 citations
Blinatumomab Added to Chemotherapy Improves Disease-Free Survival in Newly Diagnosed NCI Standard Risk Pediatric B-Acute Lymphoblastic Leukemia: Results from the Randomized Children's Oncology Group Study AALL1731
Blood2024-11-056 citations
Comparison of immunoglobulin high-throughput sequencing MRD in bone marrow and peripheral blood in pediatric B-ALL: A report from the Children's Oncology Group AALL1731.
Journal of Clinical Oncology2024-06-011 citations
Inequitable Poverty Exposures: A Subspecialty Opportunity to Address Disparities
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Improving Infectious Adverse Event Reporting in Pediatric ALL
Oncology Times2022-11-15
A Structural Racism Framework to Guide Health Equity Interventions in Pediatric Oncology
PEDIATRICS2022-04-0712 citations