Mepolizumab 100 MG

DRUG11 trials

Conditions

AsthmaAsthma Severe Persistent UncontrolledCOPDChronic Rhinosinusitis (CRS)Chronic Rhinosinusitis With Nasal PolypsChronic Rhinosinusitis With Nasal Polyps (CRSwNP)Chronic Rhinosinusitis Without Nasal PolypsDermatitis, Atopic

Phase 2

Efficacy and Safety Study of Mepolizumab in Subjects With Moderate to Severe Atopic Dermatitis

TerminatedNCT03055195

GlaxoSmithKlineDermatitis, Atopic

Start: 2017-03-21End: 2017-12-06Updated: 2020-02-25

Mepo for Eosinophilic Esophagitis (EoE) Study

CompletedNCT03656380

University of North Carolina, Chapel HillEoE, Eosinophilic Esophagitis

Start: 2019-03-20End: 2022-12-09Updated: 2023-08-23

Immunological Basis for Mepolizumab Activity in COPD

NCT05320939

Temple UniversityCOPD

Start: 2023-04-30End: 2025-05-31Target: 30Updated: 2023-04-07

Phase 3

A Pilot Study of the Use of 129Xe and 1H MRI to Measure the Modulation of Eosinophil-Related Inflammation by Mepolizumab In COPD

CompletedNCT05138250

Sheffield Teaching Hospitals NHS Foundation TrustCOPD

Start: 2022-05-08End: 2025-05-08Updated: 2026-05-07

Phase 4

Mepolizumab and in Office-office Nasal Polypectomy in Patients With Chronic Rhinosinusitis (CRS).

RecruitingNCT07814924

Instituto de Investigación Marqués de ValdecillaChronic Rhinosinusitis With Nasal Polyps

Start: 2024-12-31End: 2026-12-31Target: 75Updated: 2026-09-11

Unknown Phase

Effect of Mepolizumab on Severe Eosinophilic Asthma

NCT04641741

Hospital Clinico Universitario de SantiagoAsthma, Eosinophilic Asthma

Start: 2021-04-01End: 2025-03-01Target: 30Updated: 2023-09-25

Severe Asthma Exacerbations and Mepolizumab Treatment

NCT04914078

Università degli Studi di FerraraSevere Asthma

Start: 2021-09-21End: 2023-12-01Target: 70Updated: 2022-05-18

Role of Epithelial Barrier Integrity in Biologic Treatment Response of Severe Asthmatics With/Out Chronic Rhinosinusitis With Nasal Polyps (CRSwNP).

RecruitingNCT05365841

University of CreteSevere Eosinophilic Asthma w/wo CRSwNP

Start: 2022-05-15End: 2025-11-16Target: 85Updated: 2024-01-18

Use of Nucala in Severe Asthma

CompletedNCT05441059

Frisius Medisch CentrumAsthma Severe Persistent Uncontrolled

Start: 2021-01-01End: 2022-05-01Updated: 2022-07-01

Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic Asthma

Active, not recruitingNCT06069310

National and Kapodistrian University of AthensChronic Rhinosinusitis With Nasal Polyps, Chronic Rhinosinusitis Without Nasal Polyps, Severe Eosinophilic Asthma

Start: 2023-09-01End: 2027-03-30Updated: 2026-04-17

Real-life Evaluation of the Efficacy of Biologicals in Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)

RecruitingNCT06683261

Universitaire Ziekenhuizen KU LeuvenChronic Rhinosinusitis (CRS), Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Start: 2022-09-23End: 2026-12-31Target: 300Updated: 2024-11-12

Related Papers

Research Communication: Mepolizumab Improves Histologic Severity as Measured by the <scp>EoEHSS</scp> in Adolescents and Adults With Eosinophilic Oesophagitis in a Multicenter, Randomised, Double‐Blind, Placebo‐Controlled Clinical Trial

Alimentary Pharmacology & Therapeutics2025-05-29

Mepolizumab for treatment of adolescents and adults with eosinophilic oesophagitis: a multicentre, randomised, double-blind, placebo-controlled clinical trial

Gut2023-07-0978 citations