Meningococcal C conjugate vaccine

BIOLOGICAL7 trials

Conditions

MalariaMeningococcal InfectionPrevention of Meningococcal Infection

Phase 3

Immunogenicity, Safety and Tolerability, of Chiron Meningococcal C Conjugate Vaccine Administered to Healthy Premature and Non Premature Children of 3 Months of Age

CompletedNCT00310674

NovartisPrevention of Meningococcal Infection

Start: 2004-09-30Target: 150Updated: 2007-03-13

Immunogenicity, Safety, Tolerability and Ability to Prime for Memory of Meningococcal C Conjugate Vaccine in Healthy Children

CompletedNCT00311415

Novartis VaccinesPrevention of Meningococcal Infection

Start: 2005-10-31End: 2008-04-30Updated: 2012-02-08

Efficacy of GSK Biologicals' Candidate Malaria Vaccine 257049 Against Malaria Disease in Infants and Children in Africa

CompletedNCT00866619

GlaxoSmithKlineMalaria

Start: 2009-03-27End: 2014-01-31Updated: 2019-10-09

Phase 4

Safety, Tolerability and Immunogenicity of Meningococcal C Conjugate Vaccine to Children 32 to 40 Months of Age

CompletedNCT00310635

NovartisMeningococcal Infection

Start: 2005-06-30Target: 241Updated: 2006-10-26

Kinetics of B Cell Response in Infants Menjugate Vaccination

CompletedNCT00310700

NovartisPrevention of Meningococcal Infection

Start: 2005-05-31End: 2005-11-30Target: 75Updated: 2014-09-19

Persistence of Antibodies and Kinetics of B Cell Response in Healthy Children After Vaccination With MCC Vaccine

CompletedNCT00310713

Novartis VaccinesPrevention of Meningococcal Infection

Start: 2006-04-30End: 2006-08-31Updated: 2014-09-19

Persistence of Antibody Response to N. Meningitidis Group C in Children

CompletedNCT00316654

Novartis VaccinesPrevention of Meningococcal Infection

Start: 2005-02-28End: 2005-10-31Updated: 2017-07-25

2023-12-191 citations

Background malaria incidence and parasitemia during the three-dose RTS,S/AS01 vaccination series do not reduce magnitude of antibody response nor efficacy against the first case of malaria

BMC Infectious Diseases2023-10-238 citations

Understanding the role of serological and clinical data on assessing the dynamic of malaria transmission: a case study of Bagamoyo district, Tanzania.

2022-10-071 citations

Malaria Transmission Intensity Likely Modifies RTS, S/AS01 Efficacy Due to a Rebound Effect in Ghana, Malawi, and Gabon

The Journal of Infectious Diseases2022-07-2811 citations

Potential effect modification of RTS,S/AS01 malaria vaccine efficacy by household socio-economic status.

2021-01-287 citations

RTS,S/AS01E malaria vaccine induces IgA responses against CSP and vaccine-unrelated antigens in African children in the phase 3 trial

Vaccine2020-12-2514 citations

Environmental modifiers of RTS,S/AS01 malaria vaccine efficacy in Lilongwe, Malawi

UNC Libraries2020-10-03

Environmental modifiers of RTS,S/AS01 malaria vaccine efficacy in Lilongwe, Malawi.

2020-06-1210 citations

Safety and immunogenicity of the RTS,S/AS01 malaria vaccine in infants and children identified as HIV-infected during a randomized trial in sub-Saharan Africa.

2019-11-0718 citations

RTS,S/AS01E immunization increases antibody responses to vaccine-unrelated Plasmodium falciparum antigens associated with protection against clinical malaria in African children: a case-control study.

2019-08-1431 citations

Safety profile of the RTS,S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa

Human Vaccines & Immunotherapeutics2019-04-2365 citations

The Ethics of End-of-Trial Obligations in a Pediatric Malaria Vaccine Trial: The Perspectives of Stakeholders From Ghana and Tanzania

Journal of Empirical Research on Human Research Ethics2018-05-135 citations

The Ethics of Health Care Delivery in a Pediatric Malaria Vaccine Trial: The Perspectives of Stakeholders From Ghana and Tanzania

Journal of Empirical Research on Human Research Ethics2017-11-289 citations

Defining Health Research for Development: The perspective of stakeholders from an international health research partnership in Ghana and Tanzania.

2017-05-0310 citations

Potential public health impact of RTS,S malaria candidate vaccine in sub-Saharan Africa: a modelling study.

2015-12-2314 citations

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial.

2015-04-231132 citations

Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine during 18 Months after Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites

PLoS Medicine2014-07-29474 citations

Complex realities: community engagement for a paediatric randomized controlled malaria vaccine trial in Kilifi, Kenya.

2014-02-2564 citations

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants.

2012-11-09571 citations

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children.

2011-10-18666 citations

4 more papers not shown

Meningococcal C conjugate vaccine

Sponsors

Conditions

Phase 3

Phase 4

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