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MenACYW conjugate vaccine

BIOLOGICAL9 trials

Sponsors

Sanofi Pasteur, a Sanofi Company, Sanofi

Conditions

Healthy VolunteersHealthy Volunteers (Meningococcal Infection)Meningitis, MeningococcalMeningococcal ImmunisationMeningococcal ImmunizationMeningococcal InfectionMeningococcal Infections

Phase 1

Study of an Investigational Pentavalent Meningococcal ABCYW Vaccine in Adults and Adolescents
CompletedNCT06128733
Sanofi Pasteur, a Sanofi CompanyHealthy Volunteers, Meningococcal Immunisation
Start: 2023-10-31End: 2025-08-27Updated: 2026-01-13
Safety and Immunogenicity of an Investigational Pentavalent Meningococcal ABCYW Vaccine Against Meningococcal Disease in Children, Toddlers, and Infants
Active, not recruitingNCT06647407
Sanofi Pasteur, a Sanofi CompanyHealthy Volunteers, Meningococcal Immunization
Start: 2024-11-05End: 2027-05-17Target: 750Updated: 2026-01-20

Phase 3

Immunogenicity and Safety of a Meningococcal Conjugate Vaccine Given Concomitantly With Other Vaccines in Toddlers
CompletedNCT03205371
Sanofi Pasteur, a Sanofi CompanyMeningitis, Meningococcal
Start: 2016-11-07End: 2018-07-19Updated: 2022-04-05
Immunogenicity and Safety of a Booster Dose of a Quadrivalent Meningococcal Conjugate Vaccine in Children
CompletedNCT03476135
Sanofi Pasteur, a Sanofi CompanyMeningococcal Infections
Start: 2018-02-27End: 2018-09-10Updated: 2022-04-06
Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US
CompletedNCT03537508
Sanofi Pasteur, a Sanofi CompanyHealthy Volunteers (Meningococcal Infection)
Start: 2018-04-25End: 2023-09-22Updated: 2024-10-15
Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine When Co-administered With Routine Pediatric Vaccines in Healthy Infants and Toddlers in Europe
CompletedNCT03547271
Sanofi Pasteur, a Sanofi CompanyMeningococcal Infections
Start: 2018-12-14End: 2023-05-24Updated: 2025-03-03
Study on Immunogenicity and Safety of a Meningococcal ACYW Conjugate Vaccine in Healthy Infants and Toddlers
CompletedNCT06284915
Sanofi Pasteur, a Sanofi CompanyHealthy Volunteers, Meningococcal Immunisation
Start: 2024-03-19End: 2025-11-14Updated: 2025-12-02
Immunogenicity and Safety Study of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Administered in Healthy Children and Adolescents in China
RecruitingNCT07135986
SanofiHealthy Volunteers, Meningococcal Infection
Start: 2025-09-26End: 2026-11-02Target: 1602Updated: 2026-03-02

Phase 4

Study of Immunogenicity and Safety of MenQuadfi® as a Booster Vaccine in Toddlers 12 to 23 Months, Regardless of the Quadrivalent Meningococcal Conjugate Vaccine Used for Priming in Infancy
CompletedNCT05929651
Sanofi Pasteur, a Sanofi CompanyHealthy Volunteers, Meningococcal Immunisation
Start: 2023-09-07End: 2024-09-09Updated: 2025-09-22

Related Papers

A Phase 3 study to assess the safety and immunogenicity of a quadrivalent meningococcal conjugate vaccine (MenACYW-TT) co-administered with routine pediatric vaccines in healthy infants in the USA and Puerto Rico.
2025-12-03
Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW-TT) Administered with Routine Pediatric Vaccines: A European Randomized Controlled Trial
Infectious Diseases and Therapy2025-07-151 citations
221. Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW-TT) when Co-administered with Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US and Puerto Rico
Open Forum Infectious Diseases2025-01-292 citations
A Phase 3 study to assess the safety and immunogenicity of a quadrivalent meningococcal conjugate vaccine (MenACYW-TT) co-administered with routine pediatric vaccines in healthy infants in the USA and Puerto Rico
OPAL (Open@LaTrobe) (La Trobe University)2025-01-01
A Phase 3 study to assess the safety and immunogenicity of a quadrivalent meningococcal conjugate vaccine (MenACYW-TT) co-administered with routine pediatric vaccines in healthy infants in the USA and Puerto Rico
2025-01-01
Immunogenicity and Safety of a Quadrivalent Meningococcal Tetanus Toxoid-Conjugate Vaccine (MenACYW-TT) Administered Concomitantly with Pneumococcal Conjugate Vaccine in Healthy Toddlers in the Russian Federation: a Phase III Randomized Study
Epidemiology and Vaccinal Prevention2023-01-092 citations
Immunogenicity and safety of an investigational quadrivalent meningococcal conjugate vaccine administered as a booster dose in children vaccinated against meningococcal disease 3 years earlier as toddlers: A Phase III, open-label, multi-center study
Human Vaccines & Immunotherapeutics2021-06-0416 citations
Immunogenicity and safety of a quadrivalent meningococcal tetanus toxoid-conjugate vaccine administered concomitantly with other paediatric vaccines in toddlers: a phase III randomised study
Epidemiology and Infection2021-01-0114 citations