MEGF0444A

DRUG4 trials

Sponsors

Genentech, Inc.

Conditions

Metastatic Colorectal CancerNon-Squamous Non-Small Cell Lung CancerSolid Cancers

Phase 1

A Study of the Safety and Pharmacokinetics of MEGF0444A Administered to Patients With Advanced Solid Tumors

CompletedNCT00909740

Genentech, Inc.Solid Cancers

Start: 2009-05-22End: 2011-10-26Updated: 2022-12-12

A Study of the Safety and Pharmacology of MEGF0444A in Combination With Bevacizumab With or Without Paclitaxel in Patients With Locally Advanced or Metastatic Solid Tumors

CompletedNCT01075464

Genentech, Inc.Solid Cancers

Start: 2010-02-28End: 2013-04-30Updated: 2016-11-02

Phase 2

Study Evaluating the Safety and Efficacy of MEGF0444A in Combination With Carboplatin, Paclitaxel and Bevacizumab in Patients With Advanced or Recurrent Non-Squamous Non-Small Cell Lung Cancer Who Have Not Received Prior Chemotherapy for Advanced Disease (NILE)

CompletedNCT01366131

Genentech, Inc.Non-Squamous Non-Small Cell Lung Cancer

Start: 2011-06-30Updated: 2016-11-02

A Study Evaluating the Efficacy and Safety of MEGF0444A Dosed to Progression in Combination With Bevacizumab and mFOLFOX-6 in Participants With Previously Untreated Metastatic Colorectal Cancer

CompletedNCT01399684

Genentech, Inc.Metastatic Colorectal Cancer

Start: 2011-11-30End: 2014-02-28Updated: 2016-08-26