Mefenamic acid

DRUG11 trials

Conditions

COVID-19 COVID-19 SARS-CoV2Diabetes MellitusDrug InteractionDysmenorrhea PrimaryEndometriomaHealthy ParticipantsHealthy VolunteersIrreversible Pulpitis

Phase 1

Interaction Study to Evaluate the Effects of Mefenamic Acid on the Pharmacokinetics and Pharmacodynamics of Sotagliflozin in Healthy Male and Female Subjects

CompletedNCT03070678

SanofiDiabetes Mellitus

Start: 2017-03-14End: 2017-04-18Updated: 2022-04-25

Drug-Drug Interaction Study to Evaluate the Effect of Inhibition of UGTs on the PK of Ecopipam and Its Active Metabolite

CompletedNCT04902105

Emalex Biosciences Inc.Drug Interaction

Start: 2021-05-13End: 2021-07-06Updated: 2021-07-22

A Study of Soticlestat With Itraconazole and Mefenamic Acid in Healthy Adults

CompletedNCT05064449

TakedaHealthy Volunteers

Start: 2021-10-14End: 2021-11-30Updated: 2023-10-03

A Trial Investigating Lu AF28996 in Healthy Adult Participants

CompletedNCT06277609

H. Lundbeck A/SHealthy Participants

Start: 2024-02-27End: 2024-05-19Updated: 2024-06-11

Phase 2

DLBS1442 for The Treatment of Pain in Patients Suspected Endometriosis

CompletedNCT01942122

Dexa Medica GroupEndometrioma, Visual Analogue Pain Scale: Moderate or Severe Pain

Start: 2015-10-31End: 2021-04-30Updated: 2022-01-27

Efficacy of Different Drugs to Control Post Root Canal Treatment Pain

CompletedNCT02417337

University of KhartoumIrreversible Pulpitis, Pain, Postoperative Pain

Start: 2012-08-31End: 2015-01-31Updated: 2015-04-15

Preemptive Analgesia for Primary Dysmenorrhoea

CompletedNCT03323671

Hanan NabilPrimary Dysmenorrhea

Start: 2017-08-01End: 2017-12-01Updated: 2017-12-19

Mefenamic acid as a treatment for COVID-19

Active, not recruitingRPCEC00000388

Medical School of the University of Colima, MexicoCOVID-19 COVID-19 SARS-CoV2

Start: 2020-08-01Target: 40Updated: 2026-03-30

Phase 3

Phenamate in the treatment of prostate cancer

Active, not recruitingRPCEC00000248

Medical School of the University of Colima, MexicoProstate cancer with resistance to castration. Prostate cancer

Start: 2017-12-01Target: 40Updated: 2026-03-30

Phase 4

Management of Initial Bleeding/Spotting Associated With the Levonorgestrel-releasing Intrauterine System (MIRENA)

CompletedNCT01295294

BayerUterine Hemorrhage

Start: 2011-03-31End: 2011-12-31Updated: 2014-11-04

Vitamin E Plus Mefenamic Acid Versus Mefenamic Acid Alone for Treating Primary Dysmenorrhea in Women

CompletedNCT07466342

Nishtar Medical UniversityDysmenorrhea Primary, Mefenamic Acid, Vitamin E

Start: 2025-07-15End: 2026-01-14Updated: 2026-03-12

British Journal of Clinical Pharmacology2024-09-231 citations

Effects of Strong Inhibition of Cytochrome P450 3A and UDP glucuronosyltransferase 1A9 and Strong Induction of Cytochrome P450 3A on the Pharmacokinetics, Safety, and Tolerability of Soticlestat: Two Drug–Drug Interaction Studies in Healthy Volunteers

Drug Metabolism and Disposition2023-12-205 citations

Decreased biochemical progression in patients with castration‑resistant prostate cancer using a novel mefenamic acid anti‑inflammatory therapy: A randomized controlled trial

Oncology Letters2020-04-0314 citations

Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.

2016-04-1232 citations

Management of initial bleeding or spotting after levonorgestrel-releasing intrauterine system placement: a randomized controlled trial.

2013-05-0116 citations