Mecamylamine

DRUG11 trials

Conditions

Alcohol DependenceAlcoholismAutistic DisorderChronic Orthostatic IntoleranceCognitionCognition in SchizophreniaDepressionDiabetic Macular Edema

Phase 1

Combinations of Pharmacologic Smoking Cessation Treatments

CompletedNCT00018187

US Department of Veterans AffairsSmoking

Start: 1998-11-30End: 2001-06-30Updated: 2009-01-21

Treatment of Orthostatic Intolerance

Active, not recruitingNCT00262470

Satish R. RajChronic Orthostatic Intolerance, Tachycardia

Start: 1997-04-30End: 2029-12-31Target: 150Updated: 2025-10-08

Placebo-Controlled Pilot Trial of Mecamylamine for Treatment of Autism Spectrum Disorders

CompletedNCT00773812

Ohio State UniversityAutistic Disorder, Pervasive Developmental Disorder

Start: 2007-07-31End: 2012-11-30Updated: 2017-01-13

Phase 2

Treatment to Quit Smoking

CompletedNCT00018161

US Department of Veterans AffairsSmoking

Start: 1997-01-31End: 2001-06-30Updated: 2009-01-21

Treatment With Mecamylamine in Smoking and Non-smoking Alcohol Dependent Patients

CompletedNCT00342563

Yale UniversityAlcoholism

Start: 2004-05-31End: 2015-07-31Updated: 2019-06-04

Safety and Efficacy of ATG003 in Patients With Wet Age-Related Macular Degeneration (AMD)

TerminatedNCT00414206

CoMentisMacular Degeneration

Start: 2007-03-31End: 2009-09-30Updated: 2010-11-23

Topical Ocular Mecamylamine in Diabetic Macular Edema (DME)

CompletedNCT00536692

CoMentisDiabetic Macular Edema

Start: 2007-09-30End: 2008-04-30Updated: 2008-04-08

Flexible Dose Titration Add-on Study to Treat Major Depressive Disorder

CompletedNCT00593879

Targacept Inc.Major Depressive Disorder

Start: 2005-02-28End: 2006-08-31Updated: 2008-01-15

Phase 3

Mecamylamine for the Treatment of Patients With Depression and Alcohol Dependence

CompletedNCT00563797

Yale UniversityAlcohol Dependence, Depression

Start: 2007-08-31End: 2014-07-31Updated: 2016-04-18

Unknown Phase

Study of the Effects of Mecamylamine and Varenicline in Schizophrenia

CompletedNCT00455650

Massachusetts General HospitalCognition in Schizophrenia

Start: 2007-03-31End: 2013-01-31Updated: 2017-03-28

Nicotinic Modulation of the Default Network

CompletedNCT01223404

University of Maryland, BaltimoreCognition, Magnetic Resonance Imaging, Mecamylamine +1

Start: 2010-10-31End: 2013-09-30Updated: 2019-08-19

Related Papers

Splanchnic Venous Compression Enhances the Effects of ß-Blockade in the Treatment of Postural Tachycardia Syndrome.

2020-07-1613 citations

Negative Affect Intensity and Hostility in Individuals With Alcohol Use Disorder With or Without Posttraumatic Stress Disorder.

2018-04-251 citations

Postural Tachycardia Syndrome and Inappropriate Sinus Tachycardia: Role of Autonomic Modulation and Sinus Node Automaticity

Journal of the American Heart Association2014-03-2453 citations

Mecamylamine for Treatment of People With Dual Diagnoses of Depression and Alcohol Dependence

Journal of Dual Diagnosis2013-10-285 citations