MDR-001

DRUG6 trials

Conditions

Healthy Volunteers (HV)Hepatic Impairment (Mild and Moderate, Child-Pugh Class A and B)Hepatic Insufficiency (MeSH ID: D048550)ObesityObesity &Amp; OverweightOverweight and Obese VolunteersOverweight and ObesityOverweight or Obesity

Phase 1

A Phase I/IIa Clinical Study to Assess the Single and Multiple Ascending Doses of MDR-001 Tablets in Healthy Participants and Obese/ Overweight Participants

RecruitingNCT06778850

MindRank AI LtdOverweight and Obese Volunteers

Start: 2023-06-09End: 2025-12-30Target: 131Updated: 2025-03-07

Phase Ib Clinical Study on the Efficacy and Safety of MDR-001 in Patients Who Are Obesity or Overweight

Not yet recruitingNCT07110766

MindRank AI LtdObesity &Amp; Overweight

Start: 2025-08-09End: 2025-10-30Target: 24Updated: 2025-08-08

Pharmacokinetics and Safety of MDR-001 in Mild and Moderate Hepatic Impairment

Not yet recruitingNCT07550634

MindRank AI LtdHepatic Impairment (Mild and Moderate, Child-Pugh Class A and B), Hepatic Insufficiency (MeSH ID: D048550)

Start: 2026-06-01End: 2026-10-30Target: 32Updated: 2026-04-24

Drug-Drug Interaction Study of MDR-001 With Rifampin and Itraconazole in Healthy Adult Participants

Not yet recruitingNCT07550621

MindRank AI LtdHealthy Volunteers (HV)

Start: 2026-05-06End: 2026-06-08Target: 28Updated: 2026-04-24

Phase 2

A Study to Evaluate the Efficacy and Safety of MDR-001 in Subjects Who Are Obesity or Overweight

Not yet recruitingNCT06606483

MindRank AI LtdObesity, Overweight and Obesity

Start: 2024-09-23End: 2025-09-30Target: 300Updated: 2024-09-24

Phase 3

A Phase III Study to Evaluate the Efficacy and Safety of MDR-001 in Adult Participants With Overweight or Obesity (MOBILE）

Not yet recruitingNCT07274137

MindRank AI LtdOverweight or Obesity

Start: 2026-02-28End: 2027-07-31Target: 738Updated: 2025-12-22

MDR-001

Sponsors

Conditions

Phase 1

Phase 2

Phase 3