Matching Placebo (Solanezumab)

DRUG2 trials

Sponsors

Washington University School of Medicine

Conditions

Alzheimers DiseaseAlzheimers Disease, FamilialDementia

Phase 2

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001

Active, not recruitingNCT01760005

Washington University School of MedicineAlzheimers Disease, Alzheimers Disease, Familial, Dementia

Start: 2012-12-01End: 2028-07-01Target: 490Updated: 2026-02-13

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation.

CompletedNCT04623242

Washington University School of MedicineAlzheimers Disease, Alzheimers Disease, Familial, Dementia

Start: 2012-12-31End: 2020-03-06Updated: 2022-09-22

Related Papers

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MRI and PET findings with long‐term gantenerumab treatment: results from the DIAN‐TU trial

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Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial.

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2023-04-0519 citations

Cerebrospinal fluid sampling for research of Alzheimer’s disease and other neurodegenerative diseases when lumbar punctures are performed by anaesthetists

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Overview of dominantly inherited AD and top‐line DIAN‐TU results of solanezumab and gantenerumab

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