Matched placebo for test product
Sponsors
Sanofi-Aventis Recherche & Developpement
Conditions
BronchiectasisChronic Obstructive Pulmonary DiseaseChronic rhinosinusitis with nasal polypsDigestive system diseasesImmune system diseasesImmune system disseasesNeurodermatitisNutritional and metabolic diseases
Phase 2
A randomized, double-blind, placebo-controlled, parallel-group, Proof-of-Concept (PoC) study to assess the efficacy, safety and tolerability of itepekimab, in participants with non-cystic fibrosis bronchiectasis
Active, not recruitingCTIS2023-508663-70-00
Start: 2024-06-18Target: 138Updated: 2026-01-21
A randomized, double blind, placebo controlled, Proof of Concept (PoC) study to assess the efficacy, safety and tolerability of itepekimab in participants with inadequately controlled chronic rhinosinusitis without nasal polyps
Active, not recruitingCTIS2024-515576-12-00
Start: 2025-03-20Target: 53Updated: 2026-01-22
A randomized, double-blind, placebo-controlled, parallel-group study to assess the efficacy, safety, and tolerability of SAR444336 in participants with microscopic colitis in clinical remission with budesonide.
RecruitingCTIS2024-519495-83-00
Start: 2025-10-28Target: 78Updated: 2025-11-07
Phase 3
A double-blinded extension study to evaluate the long-term safety and tolerability of itepekimab in patients with chronic obstructive pulmonary disease (COPD) who participated in either EFC16750 or EFC16819 clinical studies
Active, not recruitingCTIS2023-508085-15-00
Start: 2024-05-15Target: 247Updated: 2026-01-20
Randomized, double-blind, placebo-controlled, parallel-group Phase 3 study to evaluate the efficacy, safety, and tolerability of SAR440340/REGN3500/itepekimab (anti-IL-33 mAb) in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) (AERIFY-1)
CompletedCTIS2024-512013-41-00
Start: 2021-03-22End: 2025-06-24Target: 686Updated: 2025-03-25
Randomized, double-blind, placebo-controlled, parallel-group Phase 3 study to evaluate the efficacy, safety, and tolerability of SAR440340/REGN3500/itepekimab (anti-IL-33 mAb) in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD)
CompletedCTIS2024-512012-21-00
Start: 2021-04-08End: 2025-08-05Target: 747Updated: 2025-03-24
A Phase 3, randomized, double-blind, placebo-controlled, parallel-group study to investigate the efficacy and safety of dupilumab for the treatment of pruritus of Lichen Simplex Chronicus (LSC) in adults
Active, not recruitingCTIS2024-514762-39-00
Start: 2025-03-03Target: 69Updated: 2025-07-18
A Phase 3, randomized, double-blind, placebo-controlled, parallel-group study to investigate the efficacy and safety of dupilumab for the treatment of pruritus of Lichen Simplex Chronicus (LSC) in adults
RecruitingCTIS2024-514737-37-00
Start: 2025-03-06Target: 77Updated: 2025-07-18
A randomized, double blind, placebo controlled, parallel group, 52week Phase 3 trial to investigate the efficacy, safety, and tolerability of itepekimab in adult participants with inadequately-controlled chronic rhinosinusitis with nasal polyps
RecruitingCTIS2024-516814-39-00
Start: 2025-05-20Target: 131Updated: 2026-01-23
A randomized, double blind, placebo controlled, parallel group, 52week Phase 3 trial to investigate the efficacy, safety, and tolerability of itepekimab in adult participants with inadequately-controlled chronic rhinosinusitis with nasal polyps
RecruitingCTIS2024-516815-26-00
Start: 2025-05-30Target: 135Updated: 2025-11-23
A randomized, double-blind, Phase 3 study to investigate efficacy and safety of teplizumab compared with placebo in participants 1 to 25 years of age with recently diagnosed Stage 3 Type 1 Diabetes (T1D) (βETA PRESERVE)
RecruitingCTIS2024-519494-19-00
Start: 2025-12-22Target: 467Updated: 2025-11-30
A Multicenter, Multinational, Randomized, Double-blind, Placebo-Controlled, Phase 3 Maintenance Study to Evaluate the Efficacy and Safety of Duvakitug in Participants with Moderately to Severely Active Ulcerative Colitis
Not yet recruitingCTIS2025-521038-27-00
Target: 89Updated: 2026-02-10
A multicenter, multinational, randomized, double-blind, placebo-controlled Phase 3, induction study to evaluate the efficacy and safety of duvakitug in participants with moderately to severely active Ulcerative Colitis.
Not yet recruitingCTIS2025-521035-37-00
Target: 210Updated: 2026-02-10
A multicenter, multinational, randomized, double-blind, placebo-controlled Phase 3, maintenance study to evaluate the efficacy and safety of duvakitug in participants with moderately to severely active Crohn’s disease
Not yet recruitingCTIS2025-521037-86-00
Target: 114Updated: 2026-02-25
A multicenter, multinational, randomized, double-blind, placebo-controlled Phase 3, induction study to evaluate the efficacy and safety of duvakitug in participants with moderately to severely active Crohn’s Disease
Not yet recruitingCTIS2025-521036-11-00
Target: 324Updated: 2026-02-25