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Matched Placebo for Test

DRUG6 trials

Sponsors

Sanofi-Aventis Research & Development, Sanofi-Aventis Recherche & Developpement

Conditions

AsthmaColitis ulcerativeDermatitis atopicHidradenitis suppurativaSystemic lupus erythematosusType 1 diabetes mellitus

Phase 2

A randomized, double-blind, placebo controlled, dose ­finding study to assess the efficacy and safety of SAR443122 in adult patients with moderate to severe ulcerative colitis
Active, not recruitingCTIS2022-500290-14-01
Sanofi-Aventis Research & DevelopmentColitis ulcerative
Start: 2023-05-11Target: 129Updated: 2025-11-06
A randomized, double-blind, placebo-controlled, proof of concept study assessing the efficacy and safety of an anti-TNF-OX40L NANOBODY® molecule, SAR442970, in participants with moderate to severe hidradenitis suppurativa
CompletedCTIS2022-502370-17-00
Sanofi-Aventis Recherche & DeveloppementHidradenitis suppurativa
Start: 2023-11-14End: 2025-01-09Target: 51Updated: 2024-10-17
A long-term extension study to evaluate the long-term safety, tolerability, and efficacy of subcutaneous amlitelimab in adult participants with moderate-to-severe asthma who completed treatment period of previous amlitelimab asthma clinical study
Active, not recruitingCTIS2023-503385-24-00
Sanofi-Aventis Recherche & DeveloppementAsthma
Start: 2024-03-12Target: 88Updated: 2025-12-18
A 52-week randomized, double-blind, placebo-controlled, multi-center Phase 2b study with a 52-week blinded extension and an optional open-label extension—assessing the safety and efficacy of frexalimab, a CD40L-antagonist monoclonal antibody, for the preservation of pancreatic β-cell function in adults and adolescents with newly diagnosed type 1 diabetes on insulin therapy
RecruitingCTIS2022-500531-36-00
Sanofi-Aventis Recherche & DeveloppementType 1 diabetes mellitus
Start: 2024-02-02Target: 192Updated: 2026-01-09
Efficacy and safety of SAR441344 in the treatment of Systemic Lupus Erythematosus: A randomized, double blind, placebo-controlled, Phase 2, proof of concept study.
RecruitingCTIS2023-508654-26-00
Sanofi-Aventis Recherche & DeveloppementSystemic lupus erythematosus
Start: 2022-03-15Target: 44Updated: 2025-12-15

Phase 3