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Matched Placebo (Capsules)

DRUG7 trials

Sponsors

University of Dundee, Lumos Pharma, Clinical Hub for Interventional Research (CHOIR), Johns Hopkins University, Middlesex University

Conditions

Airway HyperresponsivenessAirway InflammationAlzheimer s DiseaseAsthma (Diagnosis)CCUS Clonal Cytopenia of Undetermined SignificanceChronic Kidney DiseaseClonal Cytopenia of Uncertain SignificanceClonal Hematopoiesis

Phase 1

LiO-AD: Lithium Orotate in Alzheimers Disease Feasibility, Biomarker Engagement, and Clinical Response
Not yet recruitingNCT07459959
Johns Hopkins UniversityAlzheimer s Disease
Start: 2026-10-01End: 2029-08-31Target: 40Updated: 2026-06-08

Phase 2

Modulation of Stem Cell Differentiation in Individuals With High Risk Clonal Haematopoiesis
Not yet recruitingNCT07435636
Clinical Hub for Interventional Research (CHOIR)CCUS Clonal Cytopenia of Undetermined Significance, Clonal Cytopenia of Uncertain Significance, Clonal Hematopoiesis
Start: 2026-04-13End: 2030-10-01Target: 80Updated: 2026-02-27
To Study the Efficacy and Safety of Doxercalciferol on Spinal and Femoral Density in Postmenopausal Osteopenic Women in a Long Term 2 Year Study
CompletedNCT07660536
Creighton UniversityOsteoporosis (Senile)
Start: 1989-11-14End: 1994-12-23Updated: 2026-07-01
Nicotinamide Riboside Supplementation in Chronic Kidney Disease
Not yet recruitingNCT07693543
University of California, San DiegoChronic Kidney Disease
Start: 2026-10-01End: 2028-09-30Target: 30Updated: 2026-07-15

Phase 3

Phase 3 Study of LUM-201 in Children With Growth Hormone Deficiency
RecruitingNCT06948214
Lumos PharmaGrowth Hormone Deficiency (GHD)
Start: 2026-05-20End: 2028-01-01Target: 150Updated: 2026-07-17

Phase 4

Metformin in Insulin Resistant Left Ventricular (LV) Dysfunction (TAYSIDE Trial)
CompletedNCT00473876
University of DundeeCongestive Heart Failure, Insulin Resistance
Start: 2007-08-31End: 2009-04-30Updated: 2013-06-06

Unknown Phase

Can Astaxanthin Help Manage Asthma in POlluted Areas?
RecruitingNCT07507682
Middlesex UniversityAirway Hyperresponsiveness, Airway Inflammation, Asthma (Diagnosis)
Start: 2026-05-15End: 2026-07-20Target: 25Updated: 2026-04-02

Related Papers

Amino acid homeostasis is a target of metformin therapy.
2023-06-099 citations
Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
Circulation Research2016-07-15686 citations
The effect of metformin on insulin resistance and exercise parameters in patients with heart failure.
2012-06-2772 citations