Marstacimab
Sponsors
Pfizer Inc., Pfizer, Institute of Hematology & Blood Diseases Hospital, China
Conditions
HaemophiliaHemophiliaHemophilia AHemophilia A or BHemophilia BSevere Hemophilia A
Phase 1
Phase 3
B7841007 - An Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of Marstacimab Prophylaxis in Severe (Coagulation Factor Activity <1%) Hemophilia A Participants With or Without Inhibitors or Moderately Severe to Severe Hemophilia B Participants (Coagulation Factor Activity ≤2%) With or Without Inhibitors
RecruitingCTIS2022-500470-33-00
Start: 2022-11-14Target: 27Updated: 2026-01-27
A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B
RecruitingNCT05611801
Start: 2022-12-09End: 2028-09-10Target: 100Updated: 2026-08-10
B7841008 - AN OPEN-LABEL STUDY IN PEDIATRIC (<18 YEARS OF AGE), SEVERE HEMOPHILIA A PARTICIPANTS (COAGULATION FACTOR ACTIVITY <1%) WITH OR WITHOUT INHIBITORS OR MODERATELY SEVERE TO SEVERE HEMOPHILIA B PARTICIPANTS (COAGULATION FACTOR ACTIVITY ≤2%) WITH OR WITHOUT INHIBITORS COMPARING 12 MONTHS OF HISTORICAL STANDARD TREATMENT TO MARSTACIMAB PROPHYLAXIS
RecruitingCTIS2022-500495-65-00
Start: 2023-12-06Target: 22Updated: 2025-10-10
Unknown Phase
Adult and Adolescent Hemophilia Patients Treated With Marstacimab: a Patient Experience Registry
RecruitingNCT06992076
Start: 2026-02-15End: 2028-12-31Target: 100Updated: 2026-04-29
A Study to Learn About the Study Medicine -Hympavzi in Congenital Hemophilia Patients Without Inhibitors in Japan.
Active, not recruitingNCT07161687
Start: 2025-10-30End: 2030-04-11Target: 50Updated: 2026-08-27