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Magnetic Seizure Therapy

DEVICE6 trials

Sponsors

Charite University, Berlin, Germany, Centre for Addiction and Mental Health, University of Texas Southwestern Medical Center, University of Sao Paulo, The Second Hospital of Anhui Medical University

Conditions

Bipolar DepressionDepressionDepressive DisorderElectroconvulsive TherapyMagnetic Seizure TherapyMajor Depressive DisorderMajor Depressive Disorder (MDD)Treatment Resistant Depression

Phase 2

Electro-Magnetic Convulsive Therapies for Depression: a Non-inferiority Study
Active, not recruitingNCT05054699
University of Sao PauloBipolar Depression, Major Depressive Disorder
Start: 2021-05-31End: 2026-06-30Target: 100Updated: 2026-04-23

Phase 3

Berlin Magnetic Seizure Therapy Depression Trial 01
CompletedNCT00914680
Charite University, Berlin, GermanyBipolar Depression, Unipolar Depression
Start: 2009-06-30End: 2013-05-31Target: 32Updated: 2018-07-13

Unknown Phase

Evaluating the Efficacy of Magnetic Seizure Therapy in Treatment Resistant Depression.
WithdrawnNCT01748708
Centre for Addiction and Mental HealthDepressive Disorder
Start: 2016-12-31End: 2016-12-31Updated: 2017-11-20
Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for Depression
CompletedNCT03191058
University of Texas Southwestern Medical CenterDepression, Treatment Resistant Depression, Unipolar Depression
Start: 2018-06-26End: 2024-11-22Updated: 2026-05-11
Multimodal Clinical Study of Electroconvulsive Therapy and Magnetic Seizure Therapy
RecruitingNCT07473648
The Second Hospital of Anhui Medical UniversityElectroconvulsive Therapy, Magnetic Seizure Therapy, Major Depressive Disorder
Start: 2025-09-01End: 2028-01-01Target: 200Updated: 2026-07-17
Investigating Functional Changes in the Frontotemporal Cortex of Patients With Major Depressive Disorder Following Electroconvulsive Therapy or Magnetic Seizure Therapy Using Functional Near-infrared Spectroscopy (fNIRS)
RecruitingNCT07533773
The Second Hospital of Anhui Medical UniversityMajor Depressive Disorder (MDD)
Start: 2026-04-30End: 2029-04-30Target: 60Updated: 2026-07-17

Related Papers

Confirmatory efficacy and safety trial of magnetic seizure therapy versus right unilateral ultra-brief electroconvulsive therapy in depression (CREST-MST): a randomised, double-blind, non-inferiority trial in Canada and the USA.
2026-05-01
Clinical Outcomes of Magnetic Seizure Therapy vs Electroconvulsive Therapy for Major Depressive Episode
JAMA Psychiatry2023-12-0642 citations
Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for Depression (CREST-MST): protocol for identification of novel biomarkers via neurophysiology
Trials2021-12-0111 citations
Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for Depression (CREST-MST): study protocol for a randomized non-inferiority trial of magnetic seizure therapy versus electroconvulsive therapy.
2021-11-0811 citations
Noninvasive neuromodulation of the prefrontal cortex in mental health disorders.
2021-07-1622 citations
Magnetic Seizure Therapy for Suicidality in Treatment-Resistant Depression
JAMA Network Open2020-08-1826 citations