Macitentan 10mg

DRUG4 trials

Sponsors

Actelion, Assistance Publique - Hôpitaux de Paris, University of Maryland, Baltimore

Conditions

Chronic DiseaseInoperable DiseasePulmonary EmbolismPulmonary HypertensionSystemic SclerosisThromboembolic Pulmonary HypertensionUlcers

Phase 2

Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device Implantation

CompletedNCT02554903

ActelionPulmonary Hypertension

Start: 2016-03-28End: 2020-03-13Updated: 2025-03-30

Initial Dual Oral Combination Therapy Versus Standard-of-care Initial Oral Monotherapy Prior to Balloon Pulmonary Angioplasty in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension

CompletedNCT04780932

Assistance Publique - Hôpitaux de ParisChronic Disease, Inoperable Disease, Thromboembolic Pulmonary Hypertension

Start: 2021-06-14End: 2025-07-03Updated: 2025-07-20

Phase 3

Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients

CompletedNCT01474109

ActelionSystemic Sclerosis, Ulcers

Start: 2011-12-31End: 2013-11-30Updated: 2015-01-06

Macitentan to Prevent PRVO

WithdrawnNCT05946811

University of Maryland, BaltimorePulmonary Embolism

Start: 2024-05-01End: 2028-06-01Updated: 2024-03-08

Related Papers

SOPRANO: Macitentan in patients with pulmonary hypertension following left ventricular assist device implantation

Pulmonary Circulation2024-10-014 citations

Effect of Macitentan on the Development of New Ischemic Digital Ulcers in Patients With Systemic Sclerosis

JAMA2016-05-10128 citations