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Macitentan 10 mg

DRUG11 trials

Sponsors

Actelion, Janssen Research & Development, LLC

Conditions

Chronic Thromboembolic Pulmonary Hypertension (CTEPH)Congenital Heart DiseaseCongenital Heart Disease With Fontan CirculationDigital UlcersHealthyHeart Failure With Preserved Ejection Fraction and Pulmonary Vascular DiseasePulmonary Arterial HypertensionPulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)

Phase 1

Phase 2

Phase 3

Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients
TerminatedNCT01474122
ActelionDigital Ulcers
Start: 2011-12-31End: 2014-02-28Updated: 2025-02-04
Clinical Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger Syndrome
CompletedNCT01743001
ActelionPulmonary Arterial Hypertension
Start: 2013-05-21End: 2016-12-01Updated: 2018-02-23
Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Subjects
CompletedNCT03153137
ActelionCongenital Heart Disease
Start: 2017-08-14End: 2021-07-26Updated: 2025-03-30
An Upcoming Clinical Study to Measure the Safety and Impact of a Drug Called Macitentan in Teenage and Adult Fontan Patients.
TerminatedNCT03775421
ActelionCongenital Heart Disease With Fontan Circulation
Start: 2019-04-11End: 2022-01-18Updated: 2023-03-07
A Clinical Study to Find Out if Macitentan is Effective and Safe in Japanese Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH).
TerminatedNCT03809650
ActelionChronic Thromboembolic Pulmonary Hypertension (CTEPH)
Start: 2019-01-08End: 2020-06-29Updated: 2021-06-18
Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)
CompletedNCT03904693
ActelionPulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
Start: 2019-07-29End: 2024-09-27Updated: 2025-12-19
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension
Active, not recruitingNCT04273945
ActelionPulmonary Arterial Hypertension
Start: 2020-06-30End: 2029-02-20Updated: 2026-03-13

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