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MabThera 1400 mg solution for subcutaneous injection

DRUG8 trials

Sponsors

University Hospital Of Ulm AöR, Lysarc, Cellectis, LYSARC, Association International Extranodal Lymphoma Study Group (IELSG)

Conditions

Antineutrophil cytoplasmic antibody (ANCA)- associated vasculitis (AAV)Diffuse Large B-Cell LymphomaExtranodal Marginal Zone LymphomaPreviously untreated and symptomatic patients with histologically proven CD20-positive marginal zone B-cell lymphoma (MZL) in need of systemic treatmentRelapsed or refractory B-cell Acute Lymphoblastic LeukemiaRelapsed or Refractory Marginal Zone LymphomaUntreated FLIPI 2-5 Follicular LymphomaWaldenström’s Macroglobulinemia

Phase 1

Phase 2

VERLEN - Phase II, Open-Label Study evaluating efficacy of Lenalidomide and Tafasitamab combination associated to Rituximab in frontline Diffuse Large B-Cell Lymphoma Patients of 80 y/o or older
Active, not recruitingCTIS2023-507286-25-00
LYSARCDiffuse Large B-Cell Lymphoma
Start: 2021-12-23Target: 45Updated: 2025-12-30
MALIBU trial - Phase II study of combination ibrutinib and rituximab in untreated marginal zone lymphomas
Active, not recruitingCTIS2023-507886-25-00
Association International Extranodal Lymphoma Study Group (IELSG)Previously untreated and symptomatic patients with histologically proven CD20-positive marginal zone B-cell lymphoma (MZL) in need of systemic treatment
Start: 2019-09-27Target: 178Updated: 2025-06-30
A PHASE II STUDY OF CHLORAMBUCIL IN COMBINATION WITH SUBCUTANEOUS RITUXIMAB FOLLOWED BY MAINTENANCE THERAPY WITH SUBCUTANEOUS RITUXIMAB IN PATIENTS WITH EXTRANODAL MARGINAL ZONE B-CELL LYMPHOMA OF MUCOSA ASSOCIATED LYMPHOID TISSUE (MALT LYMPHOMA)
Active, not recruitingCTIS2023-507291-52-00
Association International Extranodal Lymphoma Study Group (IELSG)Extranodal Marginal Zone Lymphoma
Start: 2014-03-24Target: 106Updated: 2025-11-25
Efficacy of first line Bortezomib, Rituximab, Ibrutinib (B-RI) for patients with treatment naive Waldenström’s Macroglobulinemia - A MULTICENTER OPEN LABEL, SINGLE ARM EUROPEAN PHASE II STUDY (ECWM-2)
Active, not recruitingCTIS2022-500584-12-00
University Hospital Of Ulm AöRWaldenström’s Macroglobulinemia
Start: 2019-09-11Target: 53Updated: 2025-10-09
RemiRit - Personalized immunosuppressive therapy with rituximab in the treatment of ANCA associated vasculitis - a randomized, multicenter clinical trial
Active, not recruitingCTIS2024-517881-40-00
Wojskowy Instytut Medyczny Panstwowy Instytut BadawczyAntineutrophil cytoplasmic antibody (ANCA)- associated vasculitis (AAV)
Start: 2022-11-27Target: 130Updated: 2024-11-24

Phase 3