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Lymphodepletion Chemotherapy

DRUG2 trials

Sponsors

Jennifer Crombie, MD, Marcela V. Maus, M.D.,Ph.D.

Conditions

Antineutrophil Cytoplasmic Antibody-associated VasculitisEpstein-Barr Virus Positive Diffuse Large B-Cell LymphomaPrimary Mediastinal Large B Cell LymphomaPrimary Mediastinal Large B-Cell Lymphoma RecurrentPrimary Mediastinal Large B-Cell Lymphoma RefractoryPrimary Mediastinal Large B-cell Lymphoma (PMBCL)T-Cell/Histiocyte-Rich Large B-Cell Lymphoma

Phase 1

CC-97540 in Patients With Antineutrophil Cytoplasmic Antibody-associated Vasculitis
Active, not recruitingNCT07388277
Marcela V. Maus, M.D.,Ph.D.Antineutrophil Cytoplasmic Antibody-associated Vasculitis
Start: 2026-03-30End: 2029-12-31Target: 12Updated: 2026-09-10

Phase 2

Pembro Plus CAR T-cell Therapy in R/R in PMBCL
RecruitingNCT05934448
Jennifer Crombie, MDEpstein-Barr Virus Positive Diffuse Large B-Cell Lymphoma, Primary Mediastinal Large B Cell Lymphoma, Primary Mediastinal Large B-cell Lymphoma (PMBCL) +3
Start: 2023-11-15End: 2031-06-06Target: 35Updated: 2026-03-05