Lutikizumab
Sponsors
AbbVie Deutschland GmbH & Co. KG, AbbVie
Conditions
Atopic DermatitisCrohn's DiseaseHidradenitis SuppurativaModerate to Severe Crohn’s DiseasePsoriatic ArthritisRheumatoid ArthritisUlcerative Colitis
Phase 2
A Study to Assess Disease Activity and Safety of Subcutaneous Lutikizumab (ABT-981) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-Tumor Necrosis Factor (TNF) Therapy and Who Are Naïve to Biologic Therapy
Active, not recruitingNCT05139602
Start: 2021-12-28End: 2027-12-01Updated: 2026-02-13
A Study to Assess Adverse Events and Change in Disease Activity From Intravenous (IV) and Subcutaneous (SC) Lutikizumab in Adult Participants With Active Ulcerative Colitis
Active, not recruitingNCT06257875
Start: 2024-03-23End: 2027-09-30Updated: 2025-10-07
A Multicenter, Randomized Study to Evaluate the Safety and Efficacy of Lutikizumab for Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis
RecruitingCTIS2023-505678-14-00
Start: 2024-08-19Target: 96Updated: 2026-01-19
A Study to Assess Molecular Changes in Adult Participants With Moderate to Severe Hidradenitis Suppurativa or With Moderate to Severe Atopic Dermatitis Receiving Subcutaneous Injections of Lutikizumab
RecruitingNCT06524635
Start: 2024-08-14End: 2027-02-28Target: 60Updated: 2025-01-24
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
RecruitingNCT06548542
Start: 2024-09-04End: 2028-08-01Target: 540Updated: 2026-04-01
A Phase 2a Multicenter, Randomized, Platform Study of Targeted Therapies for the Treatment of Adult Subjects with Moderate to Severe Crohn’s Disease
RecruitingCTIS2024-513009-30-00
Start: 2024-11-21Target: 572Updated: 2025-10-14
A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis
Active, not recruitingNCT06718101
Start: 2024-12-19End: 2027-05-01Updated: 2026-02-23
Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis
RecruitingNCT06865105
Start: 2025-04-11End: 2028-01-31Target: 120Updated: 2025-12-18
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
RecruitingNCT06972446
Start: 2025-06-20End: 2027-11-01Target: 180Updated: 2026-03-27
A Phase 2 Multicenter, Randomized, Platform Study of Targeted Therapies for the Treatment of Adult Subjects with Active Psoriatic Arthritis
RecruitingCTIS2024-519291-11-00
Start: 2025-07-25Target: 63Updated: 2025-11-12
A Phase 2, Multicenter, Platform Study of Targeted Therapies for the Treatment of Adult Subjects with Moderately to Severely Active Rheumatoid Arthritis.
RecruitingCTIS2025-520721-21-00
Start: 2025-10-20Target: 108Updated: 2026-01-19
Phase 3
A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
RecruitingNCT06468228
Start: 2024-06-27End: 2026-12-01Target: 1280Updated: 2026-03-20
A Phase 3 Multicenter, Randomized, Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Lutikizumab (ABT-981) in Adult and Adolescent Subjects with Moderate to Severe Hidradenitis Suppurativa
RecruitingCTIS2024-510730-40-00
Start: 2024-12-12Target: 500Updated: 2026-01-09