Lung Clearance Index

DEVICE4 trials

Sponsors

The Hospital for Sick Children, University of North Carolina, Chapel Hill, Indiana University, Birmingham Women's and Children's NHS Foundation Trust

Conditions

AsthmaBronchiectasis AdultCystic FibrosisCystic Fibrosis in ChildrenHealthy ChildrenLung Clearance Index

Early Phase 1

19F MRI of Ventilation in Subjects With Cystic Fibrosis Undergoing Treatment for Pulmonary Exacerbation

TerminatedNCT03497117

University of North Carolina, Chapel HillCystic Fibrosis

Start: 2015-08-25End: 2019-09-13Updated: 2020-10-09

Phase 2

Xenon-129 and Inert Fluorinated Gas Lung MRI: Study of Healthy Volunteers and Participants With Pulmonary Disease

RecruitingNCT02740868

The Hospital for Sick ChildrenAsthma, Cystic Fibrosis

Start: 2015-08-01End: 2026-12-31Target: 30Updated: 2026-03-02

Unknown Phase

Determinants of Early Cystic Fibrosis Lung Disease

CompletedNCT03579173

Indiana UniversityCystic Fibrosis in Children

Start: 2018-05-08End: 2019-02-06Updated: 2022-06-22

The Utility of Lung Clearance Index in Ethnic Groups and in Disease

CompletedNCT05989360

Birmingham Women's and Children's NHS Foundation TrustBronchiectasis Adult, Healthy Children, Lung Clearance Index

Start: 2020-03-11End: 2022-09-01Updated: 2023-08-14

Related Papers

Correlation of Hyperpolarised Xenon-129 Magnetic Resonance Imaging (129Xe-MRI) of the Lung with Multi-Breath Washout (MBW) in Children with Severe Asthma

2020-09-073 citations