LSD
Sponsors
University Hospital, Basel, Switzerland, Psychiatric University Hospital, Zurich, Felix Mueller, Maastricht University, University of Chicago
Conditions
Alcohol Use Disorder (AUD)Anxiety DisordersDepressionHealthyLSDLSD ReactionLiver CirrhosisMajor Depression
Early Phase 1
Psychological, Physiological, Endocrine, and Pharmacokinetic Effects of LSD in a Controlled Study
CompletedNCT01878942
Start: 2013-06-30End: 2014-12-31Updated: 2016-01-21
Neuronal Correlates of Altered States of Consciousness
CompletedNCT02308969
Start: 2014-12-31End: 2015-09-30Updated: 2015-09-25
Role of Dopamine, Serotonin and 5-HT2A Receptors in Emotion Processing
CompletedNCT03019822
Start: 2017-02-01End: 2018-09-04Updated: 2018-10-15
Role of the Serotonin 5-HT2A Receptor in LSD-induced Altered States of Consciousness (LDR-Study)
CompletedNCT03321136
Start: 2017-11-28End: 2019-07-11Updated: 2019-08-28
Direct Comparison of Altered States of Consciousness Induced by LSD and Psilocybin
CompletedNCT03604744
Start: 2019-03-27End: 2021-04-15Updated: 2021-04-27
Mood Effects of Serotonin Agonists: Depression
RecruitingNCT07017478
Start: 2025-06-09End: 2026-06-01Target: 48Updated: 2025-07-03
Drug Effects on Mood and Behavior - Expectancy
RecruitingNCT07061886
Start: 2025-06-26End: 2026-06-05Target: 48Updated: 2025-07-11
Phase 1
Comparative Acute Effects of LSD, Psilocybin and Mescaline
CompletedNCT04227756
Start: 2020-05-19End: 2022-09-02Updated: 2024-01-24
The Effect of LSD on Neural Synchrony, Prosocial Behavior, and Relationship Quality
NCT05670184
Start: 2023-01-01End: 2024-01-01Target: 60Updated: 2023-01-04
Direct Comparison of Altered States of Consciousness Induced by LSD, Psilocybin, and DMT in Healthy Participants
RecruitingNCT06899334
Start: 2025-04-01End: 2026-08-01Target: 24Updated: 2025-03-27
Shortened LSD Intervention for Major Depressive Disorder
Not yet recruitingNCT07503002
Start: 2026-07-01End: 2027-12-01Target: 10Updated: 2026-04-03
Phase 2
LSD Treatment in Persons Suffering From Anxiety Symptoms in Severe Somatic Diseases or in Psychiatric Anxiety Disorders
CompletedNCT03153579
Start: 2017-06-23End: 2021-12-15Updated: 2021-12-22
LSD Therapy for Persons Suffering From Major Depression
CompletedNCT03866252
Start: 2019-11-01End: 2022-12-01Updated: 2025-04-23
LSD Treatment for Persons With Alcohol Use Disorder
Not yet recruitingNCT05474989
Start: 2024-06-01End: 2028-05-01Target: 126Updated: 2023-10-18
Unknown Phase
The Role of 5-HT2A Receptor in the Perception of Self and Personal Meaning in Healthy Volunteers
CompletedNCT02451072
Start: 2015-03-31End: 2016-01-31Updated: 2016-02-01
Pharmacokinetics of Didehydro-LSD (DDH-LSD) Compared With LSD
RecruitingNCT07309471
Start: 2026-03-06End: 2028-07-01Target: 24Updated: 2026-03-10
Long-term Efficacy and Safety of LSD Versus TIPS for Cirrhotic Portal Hypertension Bleeding and Hypersplenism
Not yet recruitingNCT07490405
Start: 2026-04-01End: 2036-04-01Target: 140Updated: 2026-03-24