Low-dose colchicine at 0.5mg daily

DRUG2 trials

Sponsors

Virginia Commonwealth University, University of Texas Southwestern Medical Center

Conditions

Atherosclerotic Cardiovascular Disease (ASCVD)Chronic Kidney Disease (Stage 3)Chronic Kidney Disease Mineral and Bone DisorderDiabetesDyslipidemiaHypertensionStatin Adverse Reaction

Phase 1

Safety and Efficacy of LOw DOse COlchicine in Patients With STatin INTolerance: the LODOCO STINT Pilot Study

RecruitingNCT06874192

Virginia Commonwealth UniversityStatin Adverse Reaction

Start: 2025-03-12End: 2026-08-30Target: 30Updated: 2026-07-01

Phase 2

Reducing Inflammation to Improve Vascular and Bone Outcomes With Low-dose Colchicine in CKD

Not yet recruitingNCT07654231

University of Texas Southwestern Medical CenterAtherosclerotic Cardiovascular Disease (ASCVD), Chronic Kidney Disease Mineral and Bone Disorder, Chronic Kidney Disease (Stage 3) +3

Start: 2026-07-01End: 2027-12-31Target: 60Updated: 2026-06-22