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Low normal MAP

OTHER3 trials

Sponsors

Helsinki University Central Hospital, Jesper Kjaergaard, University of Southern Denmark

Conditions

Blood PressureHemodynamic InstabilityHypertension, Pulmonary ArterialIntensive Care UnitMechanical VentilationOut-Of-Hospital Cardiac ArrestOut-of-Hospital Cardiac ArrestOxygen Therapy

Unknown Phase

Carbon Dioxide, Oxygen and Mean Arterial Pressure After Cardiac Arrest and Resuscitation
CompletedNCT02698917
Helsinki University Central HospitalOut-of-Hospital Cardiac Arrest
Start: 2016-03-22End: 2018-05-03Updated: 2018-08-03
Blood Pressure and OXygenation Targets After OHCA
CompletedNCT03141099
Jesper KjaergaardBlood Pressure, Hemodynamic Instability, Out-of-Hospital Cardiac Arrest
Start: 2017-03-10End: 2022-03-15Updated: 2022-06-30
REstrictive Versus LIberal Oxygen Strategy and Its Effect on Pulmonary Hypertension After Out-of-hospital Cardiac Arrest (RELIEPH-study)
NCT05029167
University of Southern DenmarkHypertension, Pulmonary Arterial, Intensive Care Unit, Mechanical Ventilation +3
Start: 2017-09-11End: 2023-12-31Target: 300Updated: 2022-06-01

Related Papers

Impact of Higher Versus Lower Blood Pressure Targets on Pulmonary Vascular Hemodynamics During Intensive Care After Out-of-Hospital Cardiac Arrest.
2026-08-01
Association of MMP-9 and TIMP-1 concentration with neurological outcome after cardiac arrest and resuscitation - a substudy of the COMACARE trial.
2025-12-05
Neurofilament light chain for prognostication after cardiac arrest-first steps towards validation.
2025-08-061 citations
Impact of oxygenations targets on inflammation after out-of-hospital cardiac arrest in males and females - a substudy of the BOX trial
European Heart Journal Acute Cardiovascular Care2025-04-01
Hemodynamic Characteristics and Prognostic Implication of Modified Society for Cardiovascular Angiography and Interventions Shock Classification in Comatose Patients With Out‐of‐Hospital Cardiac Arrest
Journal of the American Heart Association2024-12-206 citations
Lower vs. higher blood pressure targets during intensive care of comatose patients resuscitated from out-of-hospital cardiac arrest—a Bayesian analysis of the BOX trial
European Heart Journal Acute Cardiovascular Care2024-12-10
Abstract Su1207: Influence of Duration of Device-based Fever Prevention on Inflammation, Vasopressor Usage, and Oxygen Consumption after Cardiac Arrest - a Substudy of a Randomized Controlled Trial
Circulation2024-11-12
Impact of Blood Pressure Targets in Patients With Heart Failure Undergoing Postresuscitation Care: A Subgroup Analysis From a Randomized Controlled Trial
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Acute kidney injury after out-of-hospital cardiac arrest.
2024-05-189 citations
Combined effects of targeted blood pressure, oxygenation, and duration of device-based fever prevention after out-of-hospital cardiac arrest on 1-year survival: post hoc analysis of a randomized controlled trial
Critical Care2024-01-1211 citations
The effect of higher or lower mean arterial pressure on kidney function after cardiac arrest: a post hoc analysis of the COMACARE and NEUROPROTECT trials.
2023-11-211 citations
Abstract 139: Targeted Blood Pressure, Oxygenation, and Duration of Device-Based Fever Prevention After Out-of-Hospital Cardiac Arrest - Effects on 1 Year Survival
Circulation2023-11-07
Serial assessments of cardiac output and mixed venous oxygen saturation in comatose patients after out-of-hospital cardiac arrest.
2023-10-2712 citations
Blood Pressure and Oxygen Targets on Kidney Injury After Cardiac Arrest
Circulation2023-10-0410 citations
Quantitative pupillometry for neuroprognostication in comatose post-cardiac arrest patients: A protocol for a predefined sub-study of the Blood pressure and Oxygenations Targets after Out-of-Hospital Cardiac Arrest (BOX)-trial.
2023-09-262 citations
Abstract 126: The Association Of Higher Or Lower Mean Arterial Pressure On Kidney Function After Cardiac Arrest: A Post-hoc Analysis Of The Comacare And Neuroprotect Trials
Circulation2022-11-08
Duration of Device-Based Fever Prevention after Cardiac Arrest
New England Journal of Medicine2022-11-0692 citations
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest
New England Journal of Medicine2022-08-27237 citations
Oxygen Targets in Comatose Survivors of Cardiac Arrest
New England Journal of Medicine2022-08-27228 citations
The “Blood pressure and oxygenation targets in post resuscitation care, a randomized clinical trial”: design and statistical analysis plan
Trials2022-02-2423 citations

11 more papers not shown