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Low Dose Naltrexone

DRUG10 trials

Sponsors

Hadassah Medical Organization, Stanford University, Santa Barbara Cottage Hospital, University of Alabama at Birmingham, Rigshospitalet, Denmark

Conditions

Alcohol UseCausalgiaChronic Neuropathic PainChronic PainComplex Regional Pain SyndromeComplex Regional Pain Syndrome Type IComplex Regional Pain Syndrome Type IICrohn's Disease

Phase 1

Trial of Low-Dose Naltrexone for Children With Pervasive Developmental Disorder (PDD)
NCT00318162
Hadassah Medical OrganizationPervasive Developmental Disorder
Target: 50Updated: 2006-05-03
St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Nalmefene
CompletedNCT03278886
Boston Medical CenterAlcohol Use, HIV Infection, Pain
Start: 2018-07-03End: 2018-12-19Updated: 2020-08-24

Phase 2

Low Dose Naltrexone in Symptomatic Inflammatory Bowel Disease
WithdrawnNCT01810185
Santa Barbara Cottage HospitalCrohn's Disease, Inflammatory Bowel Disease, Ulcerative Colitis
Start: 2013-03-31End: 2014-03-31Updated: 2014-11-20

Phase 4

Low Dose Naltrexone for Treatment of Pain in Patients With Fibromyalgia - Effect Via a Central Mechanism?
CompletedNCT02806440
Rigshospitalet, DenmarkFibromyalgia
Start: 2016-06-30End: 2022-09-01Updated: 2024-02-23
Low Dose Naltrexone Use in Patients With POTS
Not yet recruitingNCT05363514
University of CalgaryPostural Orthostatic Tachycardia Syndrome
Start: 2026-07-01End: 2030-12-01Target: 80Updated: 2026-05-01
Low Dose Naltrexone for Pain in Patients With HIV
RecruitingNCT05537935
Emory UniversityChronic Neuropathic Pain, Human Immunodeficiency Virus
Start: 2023-04-28End: 2027-06-30Target: 60Updated: 2026-04-09
Low Dose Naltrexone Therapy for Complex Regional Pain Syndrome
Enrolling by invitationNCT06306157
Hospital for Special Surgery, New YorkCausalgia, Chronic Pain, Complex Regional Pain Syndrome +2
Start: 2024-01-02End: 2026-11-30Target: 40Updated: 2025-11-26

Unknown Phase

Effects of Low Dose Naltrexone in Fibromyalgia
CompletedNCT00568555
Stanford UniversityFibromyalgia, Persian Gulf Syndrome
Start: 2007-06-30End: 2010-01-31Updated: 2015-10-21
Low Dose Naltrexone for the Treatment of Juvenile Primary Fibromyalgia Syndrome
WithdrawnNCT00855972
Stanford UniversityFibromyalgia
Start: 2010-08-31End: 2011-12-31Updated: 2015-12-11
Low Dose Naltrexone (LDN) Immune Monitoring
CompletedNCT02107014
University of Alabama at BirminghamFibromyalgia
Start: 2014-03-31End: 2014-07-31Updated: 2017-04-11

Related Papers

Pilot study of tolerability and safety of opioid receptor antagonists as novel therapies for chronic pain among persons living with HIV with past year heavy drinking: a randomized controlled trial
AIDS Care2021-03-074 citations
Low dose naltrexone for induction of remission in Crohn's disease.
2014-02-2112 citations