Lopinavir / Ritonavir

DRUG13 trials

Sponsors

Oswaldo Cruz Foundation, Kirby Institute, AbbVie (prior sponsor, Abbott), UMC Utrecht, Food and Drug Administration (FDA)

Conditions

COVID-19Community-acquired Pneumonia, Influenza, COVID-19Covid19Drug-induced QT ProlongationFavipiravirHIVHIV InfectionsHigh-Grade Anal Intraepithelial Neoplasia

Phase 1

CiPA Phase 1 ECG Biomarker Validation Study

CompletedNCT03070470

Food and Drug Administration (FDA)Drug-induced QT Prolongation, Pharmacodynamics, Pharmacokinetics

Start: 2017-03-14End: 2017-06-26Updated: 2020-01-18

Lopinavir/Ritonavir in PLWH With High-Grade AIN

RecruitingNCT05334004

University of Wisconsin, MadisonHigh-Grade Anal Intraepithelial Neoplasia

Start: 2023-12-19End: 2027-06-01Target: 21Updated: 2026-05-15

LUSZ Treatment Efficacy in Hospitalized COVID-19 Patients

RecruitingNCT05925140

Lebanese UniversityCOVID-19, Hospitalized COVID-19 Patients

Start: 2020-03-28End: 2025-12-30Target: 1000Updated: 2024-02-06

Phase 2

An Investigation Into Beneficial Effects of Interferon Beta 1a, Compared to Interferon Beta 1b And The Base Therapeutic Regiment in Moderate to Severe COVID-19: A Randomized Clinical Trial

CompletedNCT04343768

Shahid Beheshti University of Medical SciencesCOVID-19

Start: 2020-04-09End: 2020-04-27Updated: 2020-05-05

A Phase 2a Study of the Preliminary Efficacy of DARE-HPV to Treat High-risk Persistent Human Papillomavirus (hrHPV).

Not yet recruitingNCT07601074

Daré Bioscience, Inc.High-risk Human Papillomavirus Infection, Human Papilloma Virus (HPV)

Start: 2026-06-01End: 2027-12-01Target: 118Updated: 2026-05-22

Phase 3

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

RecruitingNCT02735707

UMC UtrechtCommunity-acquired Pneumonia, Influenza, COVID-19

Start: 2016-04-11End: 2028-02-29Target: 20000Updated: 2024-07-12

Phase 4

Pharmacokinetics of the Tablet Formulation of Lopinavir/r as Standard and Increased Dosage During Pregnancy

CompletedNCT00605098

Oswaldo Cruz FoundationHIV Infections, Pregnancy

Start: 2008-02-29End: 2012-07-31Updated: 2013-10-28

Bone and Body Comp: A Sub Study of the SECOND-LINE Study

CompletedNCT01513122

Kirby InstituteHIV

Start: 2010-02-28End: 2013-08-31Updated: 2025-06-26

Umifenovir in Hospitalized COVID-19 Patients

Shahid Beheshti University of Medical SciencesCOVID-19

Start: 2020-04-15End: 2020-04-24Target: 40Updated: 2020-04-20

Interferon Beta 1a in Hospitalized COVID-19 Patients

Shahid Beheshti University of Medical SciencesCOVID-19

Start: 2020-04-15End: 2020-04-24Target: 40Updated: 2020-04-20

Unknown Phase

Real-life Effectiveness of the Kaletra Adherence Support Assistance (KASA) Program

CompletedNCT01662336

AbbVie (prior sponsor, Abbott)Human Immunodeficiency Virus Infection

Start: 2012-06-30End: 2016-06-30Updated: 2018-01-29

Favipiravir Plus Hydroxychloroquine and Lopinavir/Ritonavir Plus Hydroxychloroquine in COVID-19

CompletedNCT04376814

Baqiyatallah Medical Sciences UniversityCOVID-19, Favipiravir, Hydroxychloroquine +2

Start: 2020-03-29End: 2020-05-25Updated: 2020-06-16

Public Health Emergency: SOLIDARITY TRIAL Philippines

CompletedNCT05024006

University of the PhilippinesCovid19

Start: 2020-04-23End: 2021-04-17Updated: 2022-03-02

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