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loop electrosurgical excision procedure

PROCEDURE7 trials

Sponsors

National Cancer Institute (NCI), British Columbia Cancer Agency, United States Naval Medical Center, San Diego, Centre Hospitalier Universitaire, Amiens, Instituto Nacional de Saúde, Mozambique

Conditions

BiomarkersCIN 2/3CancerCervical CancerCervical Intraepithelial NeoplasiaCervical Intraepithelial Neoplasia Grade 2Cervical Intraepithelial Neoplasia Grade 3HIV Infections

Phase 1

Photodynamic Therapy Using Lutetium Texaphyrin in Treating Patients With Cervical Intraepithelial Neoplasia
TerminatedNCT00005808
National Cancer Institute (NCI)Cervical Cancer, Cervical Intraepithelial Neoplasia Grade 2, Cervical Intraepithelial Neoplasia Grade 3
Start: 2000-12-31Updated: 2013-02-07

Phase 2

Topical Imiquimod vs. LEEP for Women With Carcinoma In-situ of the Cervix
CompletedNCT02130323
United States Naval Medical Center, San DiegoCervical Intraepithelial Neoplasia
Start: 2015-02-28End: 2017-05-09Updated: 2017-06-27
Topical 5-Fluorouracil and Imiquimod for the Treatment of High-grade Cervical Intraepithelial Neoplasia: A Randomised Open-Label Controlled Trial (TOPFIT-CIN Study)
Active, not recruitingPACTR202505720883384
College of Medicine University of LagosCancer
Start: 2025-06-02Target: 90Updated: 2026-01-27

Phase 4

Clinical Outcome and Biomarkers for Predicting Immunological Response in Patients Treated with Imiquimod
RecruitingNCT06356012
Barretos Cancer HospitalBiomarkers, HSIL, High-Grade Squamous Intraepithelial Lesions, Vaginal Microbiome
Start: 2024-04-02End: 2028-12-31Target: 96Updated: 2025-02-05

Unknown Phase

Digital Colposcopy in Finding Cervical Intraepithelial Neoplasia
CompletedNCT00602368
British Columbia Cancer AgencyCervical Cancer, Precancerous Condition
Start: 2010-12-31End: 2015-05-31Updated: 2017-02-01
Impact of Age at Conization on Obstetrical Outcome: A Case-Control Study
CompletedNCT05765188
Centre Hospitalier Universitaire, AmiensPregnancy Complications
Start: 2015-01-01End: 2017-04-02Updated: 2023-03-13
Assessment of the Effectiveness of TA Versus LEEP for Cervical Cancer Risk Reduction in WLHIV in Mozambique
RecruitingNCT06326294
Instituto Nacional de Saúde, MozambiqueCIN 2/3, HIV Infections, HPV Infection
Start: 2024-04-17End: 2027-12-31Target: 4844Updated: 2024-05-22

Related Papers

A randomized clinical trial to assess the effectiveness of thermal ablation versus loop electrosurgical excision procedure for cervical cancer risk reduction in women living with HIV in Mozambique.
2025-04-26