Long-course radiotherapy
Sponsors
Fudan University, Tao Zhang, Fujian Cancer Hospital, Beijing Friendship Hospital
Conditions
Early Low Rectal CancerImmunotherapyLocally Advanced Rectal AdenocarcinomaLocally Advanced Rectal CancerNeoadjuvant ChemoradiationNeoadjuvant ImmunotherapyNeoadjuvant TherapyRadiotherapy
Phase 2
Short-course Radiotherapy Combined With CAPOX and PD-1 Antibody Versus Long-course Chemoradiotherapy Combined With CAPOX for Early Low-lying Rectal Cancer
RecruitingNCT06462053
Start: 2024-04-01End: 2027-03-01Target: 134Updated: 2024-06-17
Long-course Chemoradiotherapy or Short-course Radiotherapy Combined With CAPOX, PD-1antibody, and COX-2 Inhibitor for MSS Locally Advanced Rectal Cancer (SERRAC)
RecruitingNCT07150949
Start: 2025-08-28End: 2028-08-31Target: 138Updated: 2025-09-02
Short-Course RT Plus CAPOX and Tislelizumab vs Long-Course CRT Plus Tislelizumab for Locally Advanced Rectal Cancer
Not yet recruitingNCT07469306
Start: 2026-08-10End: 2027-09-01Target: 130Updated: 2026-03-13
Yang et al. Anti-PD-1/CTLA-4 Dual Immunotherapy for LARC
Not yet recruitingNCT07596290
Start: 2026-05-15End: 2030-12-31Target: 342Updated: 2026-05-22