Local Therapy

PROCEDURE7 trials

Conditions

Breast CancerBreast NeoplasmsHepatic Artery Infusion ChemotherapyHepatocellular CarcinomaImmunotherapyLangerhans Cell HistiocytosisLocally Advanced Bladder Urothelial CarcinomaLocally Advanced Renal Pelvis and Ureter Urothelial Carcinoma

Phase 2

Aggressive Local Therapy for Limited Bone-Only Metastasis to Improve Progression-Free Survival in Breast Cancer Patients

Active, not recruitingNCT00929214

M.D. Anderson Cancer CenterBreast Cancer

Start: 2009-06-24End: 2027-12-01Updated: 2026-06-12

Phase II Study of Local Therapy Combined with Immune Checkpoint Inhibitor for Oligo-Progressive disease during First-line Immunotherapy in non-small cell lung cancer

RecruitingJPRN-jRCTs031220630

Shukuya TakehitoNon-small cell lung cancer Oligo-Progressive disease

Start: 2023-07-18Target: 32Updated: 2026-06-29

BITS-TO-HCC Study: HAIC+Iparomlimab/Tuvonralimab + Bevacizumab + Surgery/SBRT for BCLC-C HCC With PVTT and/or Oligometastases

RecruitingNCT07062055

Shandong Cancer Hospital and InstituteHepatic Artery Infusion Chemotherapy, Hepatocellular Carcinoma, Immunotherapy +3

Start: 2025-07-25End: 2029-07-25Target: 54Updated: 2026-09-04

Phase 3

A Prospective Study for the Treatment of Children With Newly Diagnosed LCH Using a Cytarabine Contained Protocol

RecruitingNCT04773366

Shanghai Children's Medical CenterLangerhans Cell Histiocytosis

Start: 2018-07-01End: 2026-06-30Target: 200Updated: 2022-07-26

Phase 4

Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial

RecruitingNCT06764095

Mayo ClinicLocally Advanced Bladder Urothelial Carcinoma, Locally Advanced Renal Pelvis and Ureter Urothelial Carcinoma, Metastatic Bladder Urothelial Carcinoma +4

Start: 2025-01-08End: 2034-12-31Target: 75Updated: 2026-02-12

Unknown Phase

A Study of Local Therapy for the Treatment of Brain Metastases From HER2 Positive Breast Cancer

CompletedNCT02898727

Trans Tasman Radiation Oncology GroupBreast Neoplasms

Start: 2017-11-20End: 2021-12-31Updated: 2022-11-22

Biomarker and Mechanism Study of Systemic Therapy in Unresectable HCC

Not yet recruitingNCT07786792

Shanghai Zhongshan HospitalHepatocellular Carcinoma