LLETZ

PROCEDURE6 trials

Sponsors

Maastricht University Medical Center, Erasmus Medical Center, University of Pretoria, Ruhr University of Bochum, University Medical Centre Maribor

Conditions

CIN2Cervical CancerCervical DysplasiaCervical Intraepithelial NeoplasiaHigh Grade SilIntraepithelial Neoplasia, Cervical

Phase 3

Imiquimod Treatment of CIN Lesions

TerminatedNCT02329171

Maastricht University Medical CenterCervical Intraepithelial Neoplasia

Start: 2014-12-31End: 2016-06-30Updated: 2018-08-15

Imiquimod Treatment of Residual or Recurrent CIN Lesions: a Study Protocol

Erasmus Medical CenterCervical Intraepithelial Neoplasia

Start: 2016-05-31End: 2020-03-31Target: 433Updated: 2018-02-06

Unknown Phase

Screening Study for Cervical Pre-cancer and Cancer Prevention in South African Women.

RecruitingNCT02956031

University of PretoriaCervical Cancer, CIN2, High Grade Sil

Start: 2016-12-31End: 2038-12-31Target: 1500Updated: 2025-07-08

Comparison of LLETZ Versus LEEP for the Treatment of Cervical Dysplasia

RecruitingNCT04772937

Ruhr University of BochumCervical Dysplasia

Start: 2021-06-07End: 2025-11-30Target: 206Updated: 2025-01-30

Comparison of Treatment of Cervical Intraepithelial Lesions With Imiquimod or LLETZ

University Medical Centre MariborIntraepithelial Neoplasia, Cervical

Start: 2018-11-20End: 2023-09-15Updated: 2021-05-03

Large Loop Excision of the Transformation Zone During Follicular Vs. Luteal Phase of the Menstrual Cycle (LLETZ-MC)

Not yet recruitingNCT05391243

Ruhr University of BochumCervical Dysplasia

Start: 2025-03-31End: 2026-12-31Target: 152Updated: 2025-01-31

Related Papers

Modulation of sHLA-G, PD-1, and PD-L1 Expression in Cervical Lesions Following Imiquimod Treatment and Its Association with Treatment Success

Cancers2024-03-25

Cytology compared with Hybrid Capture 2 human papilloma virus cervical cancer screening in HIV positive and HIV negative South African women.

2023-05-014 citations

TOPical Imiquimod treatment of residual or recurrent cervical intraepithelial neoplasia (TOPIC-2 trial): a study protocol for a randomized controlled trial.

2018-06-1510 citations

Preliminary stop of the TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia (TOPIC) trial.

2017-02-0712 citations

TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia (TOPIC trial): study protocol for a randomized controlled trial.

2016-02-2013 citations