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LJPC-501

DRUG3 trials

Sponsors

La Jolla Pharmaceutical Company

Conditions

Catecholamine Resistant Hypotension (CRH)Catecholamine-resistant Hypotension (CRH)Distributive ShockHepatorenal Syndrome Type I and Type IIHigh Output ShockSepsisVasodilatory Shock

Phase 1

A Phase 1 Study of LJPC-501 in Patients With Hepatorenal Syndrome
TerminatedNCT01906307
La Jolla Pharmaceutical CompanyHepatorenal Syndrome Type I and Type II
Start: 2014-03-31End: 2015-12-31Updated: 2016-03-03

Phase 3

A Phase 3 Study of LJPC-501 in Patients With Catecholamine-Resistant Hypotension
CompletedNCT02338843
La Jolla Pharmaceutical CompanyCatecholamine-resistant Hypotension (CRH), Distributive Shock, High Output Shock +1
Start: 2015-03-31End: 2017-02-18Updated: 2018-03-27

Unknown Phase

Expanded Access for LJPC-501
NCT03245528
La Jolla Pharmaceutical CompanyCatecholamine Resistant Hypotension (CRH), Distributive Shock, High Output Shock +2
Updated: 2018-03-08

Related Papers

ACE inhibitors and angiotensin receptor blockers differentially alter the response to angiotensin II treatment in vasodilatory shock.
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Initiating angiotensin II at lower vasopressor doses in vasodilatory shock: an exploratory post-hoc analysis of the ATHOS-3 clinical trial
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Renin and Survival in Patients Given Angiotensin II for Catecholamine-Resistant Vasodilatory Shock. A Clinical Trial
American Journal of Respiratory and Critical Care Medicine2020-07-01214 citations
Angiotensin I and angiotensin II concentrations and their ratio in catecholamine-resistant vasodilatory shock.
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FDA Approval of Angiotensin II for the Treatment of Hypotension in Adults with Distributive Shock.
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Angiotensin II for the Treatment of Vasodilatory Shock
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Angiotensins and Their Receptors in Cardiac and Vascular Injury.
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