liuos

DRUG14 trials

Sponsors

Charite Universitaetsmedizin Berlin KöR, HUS-Yhtymae, University Of Helsinki, Turku University Hospital, HUS-Yhtymae, Pohjois-Savon hyvinvointialue

Conditions

Acute cholecystitisBreast cancerCancerChronic Obstructive Plumonary Disease (COPD)Chronic limb-threatening ischemia (CLTI)Colon cancerDiabetic Foot OsteomyelitisHip osteoarthrosis and postoperative pain

Phase 2

A phase 2a open-label study to assess the safety, tolerability, and dosing regimen of antithrombotic heparin proteoglycan mimetic APAC (antiplatelet, anticoagulant) in patients with peripheral arterial occlusive disease and chronic limb-threatening ischemia undergoing endovascular revascularization (HEALING -study)

Not yet recruitingCTIS2025-522390-11-00

Aplagon OyChronic limb-threatening ischemia (CLTI), Peripheral arterial occlusive disease (PAOD)

Target: 42Updated: 2025-09-15

Phase 3

DPDIMP#1-trial: Impact of DPYD gene test on the safety and efficacy of fluoropyrimidine therapy

CompletedCTIS2024-518448-20-00

HUS-YhtymaeBreast cancer, Colon cancer

Start: 2019-10-17End: 2025-03-17Target: 1000Updated: 2024-10-29

A single group treatment, phase 4, study to assess the effect of 1 dose with oxymetazoline nasal spray(Otrivin®) on physical capacity of males and females aged 18 and 64 years suffering from Chronic Obstructive Pulmonary Disease (COPD)

Not yet recruitingCTIS2024-520177-12-00

Sorlandet Sykehus HFChronic Obstructive Plumonary Disease (COPD)

Target: 64Updated: 2025-01-24

Preoperative Antibiotics for Mild or Moderate Acute Cholecystitis (POMMAC): A Non-inferiority, Open-label, Randomized Controlled Trial – Study Protocol

RecruitingCTIS2024-515958-24-00

HUS-YhtymaeAcute cholecystitis

Start: 2025-08-25Target: 456Updated: 2025-12-05

International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 - A Randomized Phase III Study Conducted by the Resistant Disease Committee of the International BFM Study Group - IntReALL BCP 2020

Not yet recruitingCTIS2023-509392-17-00

Charite Universitaetsmedizin Berlin KöRRelapsed Acute Lymphoblastic Leukemia (ALL)

Target: 765Updated: 2025-12-15

LIBRETTO: Stimulan™ Local Antibiotic Delivery System Versus 4-Week Systemic Antibiotic Therapy for Diabetic Foot Osteomyelitis – A Prospective, Randomized, Controlled Trial

Not yet recruitingCTIS2025-524723-52-00

Pirkanmaan hyvinvointialueDiabetic Foot Osteomyelitis

Target: 84Updated: 2026-04-10

Phase 4

The Effect of Cancer Treatments on Speech Perception in Noise, Cognition, and Quality of Life

RecruitingCTIS2024-513437-21-00

Turku University HospitalCancer

Start: 2024-10-02Target: 250Updated: 2024-07-26

The efficacy, safety and neonatal effects of oxycodone in treatment of labour pain

Not yet recruitingCTIS2024-516495-15-00

Pohjois-Savon hyvinvointialuelabour

Target: 12Updated: 2024-08-09

Monitoring of neuromuscular blockade during general anaesthesia after reversal with neostigmine

RecruitingCTIS2024-517831-28-00

Pirkanmaan hyvinvointialueIncidence of reappearance of the muscle relaxation after reversal with neostigmine

Start: 2025-01-01Target: 120Updated: 2024-09-17

Thrombosis prophylaxis and coagulation activation during neoadjuvant treatment in pancreatic cancer - Association to prognosis and recurrence.

RecruitingCTIS2024-512475-12-01

HUS-Yhtymae, University Of HelsinkiWe are investigating the efficacy and safety of enhanced thromboprophylaxis during neoadjuvant treatments for pancreatic cancer.

Start: 2024-11-27Target: 214Updated: 2024-11-27

Lantiolihaspuudutuksen vaikutus munuaisen poistoleikkauksen jälkeiseen kivun hoitoon ja toipumiseen

Not yet recruitingCTIS2024-519910-30-00

Pirkanmaan hyvinvointialueRenal cancer

Target: 90Updated: 2025-01-21

RAXO trial - A population-based prospective study to evaluate clinical behaviour, resectability and survival in metastatic colorectal cancer patients in Finland

RecruitingCTIS2024-520288-15-00

HUS-YhtymaeMetastatic or locally advanced inoperable colorectal cancer

Start: 2025-01-25Target: 60000Updated: 2025-12-19

Premedication for Less Invasive Surfactant Administration (LISA-Med)

Not yet recruitingCTIS2025-520492-10-00

Pohjois-Pohjanmaan hyvinvointialue, University Of Oulupremedication, respiratory distress syndrome, surfactant treatment

Target: 40Updated: 2025-01-28

Post-operative analgesia and spinal block duration following total hip arthroplasties - comparison of single-shot intrathecal ropivacaine, and bupivacaine: a randomized, double blinded controlled study

Not yet recruitingCTIS2025-522358-38-02

Turku University HospitalHip osteoarthrosis and postoperative pain

Target: 158Updated: 2025-10-31