LITT

PROCEDURE5 trials

Sponsors

Case Comprehensive Cancer Center, University of Maryland, Baltimore, Beijing Tiantan Hospital, M.D. Anderson Cancer Center, Insel Gruppe AG, University Hospital Bern

Conditions

Brain MetastasesBrain TumorGlioblastomaGlioblastoma (GBM)Glioblastoma - CategoryGliomaHigh Grade GliomaRecurrent High Grade Glioma

Early Phase 1

Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas

CompletedNCT02970448

Case Comprehensive Cancer CenterHigh Grade Glioma

Start: 2017-08-24End: 2024-10-25Updated: 2026-08-06

Phase 2

Laser Interstitial Thermal Therapy (LITT) or Surgery and Adjuvant Reirradiation for Recurrent Brain Metastases (LaSAR BeaM)

RecruitingNCT07053033

M.D. Anderson Cancer CenterBrain Metastases

Start: 2026-01-01End: 2028-12-30Target: 155Updated: 2026-03-09

Unknown Phase

LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)

RecruitingNCT04699773

University of Maryland, BaltimoreBrain Tumor, Glioblastoma, Glioma

Start: 2021-02-20End: 2027-12-01Target: 32Updated: 2026-05-06

Recurrent High Grade Glioma Treated by LITT

RecruitingNCT06161610

Beijing Tiantan HospitalRecurrent High Grade Glioma

Start: 2023-09-19End: 2027-09-19Target: 135Updated: 2024-11-29

LITT for Ultra-early GBM Recurrence

RecruitingNCT07616986

Insel Gruppe AG, University Hospital BernGlioblastoma - Category, Glioblastoma (GBM)

Start: 2026-02-06End: 2028-01-31Target: 12Updated: 2026-06-01