Liposomal daunorubicin

DRUG3 trials

Sponsors

University Hospital Muenster, University of Birmingham, Sanofi

Conditions

Acute Lymphoblastic LeukemiaAcute Myeloid LeukaemiaAcute Myeloid LeukemiaMyeloid Leukemia

Phase 2

Therapy-Optimization Trial for the Treatment of Acute Myeloid Leukemias (AML) in Children and Adolescents

University Hospital MuensterMyeloid Leukemia

Start: 2004-03-31End: 2017-03-31Updated: 2012-05-23

Isatuximab in Combination With Chemotherapy in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

TerminatedNCT03860844

SanofiAcute Lymphoblastic Leukemia, Acute Myeloid Leukemia

Start: 2019-08-06End: 2023-05-26Updated: 2025-09-09

Phase 3

International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia

RecruitingNCT02724163

University of BirminghamAcute Myeloid Leukaemia

Start: 2016-04-30End: 2032-12-31Target: 700Updated: 2021-10-08

Related Papers

Selection of isatuximab dosing regimen in pediatric patients with leukemia using population pharmacokinetics.

2025-12-03

Isatuximab in combination with chemotherapy for pediatric patients with relapsed/refractory acute lymphoblastic leukemia or acute myeloid leukemia: The ISAKIDS study.

2025-10-30

Prognostic Value of Molecular Genetic Measurable Residual Disease ( <scp>MRD</scp> ) Monitoring in Pediatric Acute Myeloid Leukemia Expressing <i>KMT2A::MLLT10</i>

European Journal Of Haematology2025-08-131 citations

Outcomes for Children with High Risk Acute Myeloid Leukemia on the Myechild 01 International Phase III Clinical Trial

Blood2023-11-021 citations

P501: ISATUXIMAB PLUS CHEMOTHERAPY FOR PEDIATRIC RELAPSED/REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA OR ACUTE MYELOID LEUKEMIA (ISAKIDS): INTERIM EFFICACY ANALYSIS

HemaSphere2023-08-014 citations

Isatuximab in Combination with Chemotherapy in Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia (ISAKIDS): Interim Analysis

Blood2021-11-0510 citations

Infectious Complications in Children With Acute Myeloid Leukemia and Down Syndrome: Analysis of the Prospective Multicenter Trial AML-BFM 2004.

2016-01-2718 citations

Randomized trial comparing liposomal daunorubicin with idarubicin as induction for pediatric acute myeloid leukemia: results from Study AML-BFM 2004.

2013-05-23132 citations

Intact apoptosis signaling in myeloid leukemia cells determines treatment outcome in childhood AML.

2007-12-148 citations