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Liposomal Cyclosporine A

DRUG3 trials

Sponsors

Zambon SpA

Conditions

Bronchiolitis ObliteransBronchiolitis Obliterans Syndrome (BOS)Chronic Lung Allograft DysfunctionChronic Rejection of Lung TransplantGVHD, ChronicLung Transplant Failure and RejectionLung Transplant RejectionLung Transplant; Complications

Phase 2

A Safety Study of Liposomal Cyclosporine A to Treat Bronchiolitis After Hematopoietic Transplant (BOSTON-4)
TerminatedNCT04107675
Zambon SpABronchiolitis Obliterans Syndrome (BOS), GVHD, Chronic, Stem Cell Transplant Complications
Start: 2020-02-11End: 2022-12-15Updated: 2023-10-03

Phase 3

Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Double Lung Transplant (BOSTON-2)
CompletedNCT03656926
Zambon SpABronchiolitis Obliterans, Chronic Lung Allograft Dysfunction, Chronic Rejection of Lung Transplant +3
Start: 2019-03-26End: 2024-03-12Updated: 2026-02-10
Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-1)
CompletedNCT03657342
Zambon SpABronchiolitis Obliterans, Chronic Lung Allograft Dysfunction, Chronic Rejection of Lung Transplant +3
Start: 2019-03-26End: 2024-04-16Updated: 2025-10-27