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linifanib

DRUG7 trials

Sponsors

AbbVie, Vanderbilt-Ingram Cancer Center, Abbott, BioGene Pharmaceutical Ltd.

Conditions

Advanced Solid TumorsAdvanced or Metastatic Solid TumorsEndometriosisEndometriosis ExternaEndometriosis OvaryEndometriosis, RectumNon-Small Cell Lung CancerRecurrent Colon Cancer

Phase 1

A Study of Linifanib (ABT-869) in Combination With Carboplatin/Paclitaxel in Japanese Subjects With Non-Small Cell Lung Cancer (NSCLC)
CompletedNCT01225302
AbbVieNon-Small Cell Lung Cancer
Start: 2010-09-30End: 2012-06-30Updated: 2017-11-21
To Compare Relative Bioavailability of Two Clinical Formulations of Linifanib.
CompletedNCT01381341
AbbottAdvanced Solid Tumors
Start: 2011-05-31End: 2011-12-31Updated: 2012-03-23
Effect of Rifampin on the Pharmacokinetics of Linifanib in Subjects With Advanced or Metastatic Solid Tumors
CompletedNCT01401933
AbbottAdvanced Solid Tumors
Start: 2011-05-31End: 2011-10-31Updated: 2011-11-02
An Extension Study of Linifanib (ABT-869) in Subjects With Advanced or Metastatic Solid Tumors
CompletedNCT01413893
AbbVieAdvanced Solid Tumors
Start: 2011-06-30End: 2012-06-30Updated: 2017-11-21
A Study Evaluating the Bioavailability of Two Formulations of Linifanib and Food Effect on Pharmacokinetics of Linifanib in Subjects With Advanced or Metastatic Solid Tumors
TerminatedNCT01506934
AbbottAdvanced or Metastatic Solid Tumors
Start: 2011-10-31End: 2012-01-31Updated: 2012-08-28
Safety, Tolerability and Efficacy of Vaginal Suppositories for Treatment of the Endometriosis
WithdrawnNCT03481842
BioGene Pharmaceutical Ltd.Endometriosis, Endometriosis Externa, Endometriosis Ovary +1
Start: 2021-10-10End: 2021-10-10Updated: 2021-10-29

Phase 2

Linifanib in Treating Patients With Advanced, Refractory Colorectal Cancer
TerminatedNCT01365910
Vanderbilt-Ingram Cancer CenterRecurrent Colon Cancer, Recurrent Rectal Cancer, Stage IVA Colon Cancer +3
Start: 2011-06-30End: 2013-06-30Updated: 2014-08-26