Linagliptin 5mg

DRUG4 trials

Sponsors

Boehringer Ingelheim, Dong Wha Pharmaceutical Co. Ltd.

Conditions

Diabetes Mellitus, Type 2Healthy

Phase 1

the Pharmacokinetic Profiles of Linagliptin With DW1029M

CompletedNCT02212782

Dong Wha Pharmaceutical Co. Ltd.Healthy

Start: 2014-09-30End: 2015-01-31Updated: 2015-06-29

Phase 3

30 Week Parallel Group Comparison Study of Linagliptin + Pioglitazone (5+15, 5+30 and 5+45 mg) qd Versus Respective Monotherapies, Followed by a Comparison of 5mg+30mg and 5mg+45mg Versus Respective Monotherapies in Type 2 Diabetes for up to 54 Weeks

CompletedNCT01183013

Boehringer IngelheimDiabetes Mellitus, Type 2

Start: 2010-08-31End: 2013-02-28Updated: 2014-10-20

Study to Compare the Efficacy and Safety of Administration of the Fix Dose Combination of Linagliptin Plus Metformin in Drug naïve Type 2 Patients

CompletedNCT01708902

Boehringer IngelheimDiabetes Mellitus, Type 2

Start: 2012-10-31End: 2014-04-30Updated: 2015-04-24

MARLINA - T2D : Efficacy, Safety & Modification of Albuminuria in Type 2 Diabetes Subjects With Renal Disease With LINAgliptin

CompletedNCT01792518

Boehringer IngelheimDiabetes Mellitus, Type 2

Start: 2013-02-28End: 2015-12-31Updated: 2017-03-06

Related Papers

Early Combination Therapy with Linagliptin and Metformin in People with Type 2 Diabetes Improves Glycemic Control to HbA1c ≤ 6.5% without Increasing Hypoglycemia: Pooled Analysis of Two Randomized Clinical Trials

Diabetes Therapy2020-04-2310 citations

Urinary Proteomics as a Tool to Identify Kidney Responders to Dipeptidyl Peptidase‐4 Inhibition: A Hypothesis‐Generating Analysis from the MARLINA‐T2D Trial

PROTEOMICS - CLINICAL APPLICATIONS2019-01-1132 citations

Linagliptin and its effects on hyperglycaemia and albuminuria in patients with type 2 diabetes and renal dysfunction: the randomized MARLINA-T2D trial.

2017-07-31112 citations

A randomised, active- and placebo-controlled, three-period crossover trial to investigate short-term effects of the dipeptidyl peptidase-4 inhibitor linagliptin on macro- and microvascular endothelial function in type 2 diabetes

Cardiovascular Diabetology2017-01-2137 citations