LIK066
Sponsors
Novartis Pharmaceuticals
Conditions
Diabetes Mellitus and Heart FailureElevated Body Mass IndexObese Patients With Non-alcoholic Steatohepatitis (NASH)ObesityOverweightPolycystic Ovary SyndromeRenal ImpairmentType 2 Diabetes Mellitus
Phase 1
Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) Assessment of LIK066 in Healthy Subjects and in Patients With Type 2 Diabetes Mellitus (T2DM)
CompletedNCT01407003
Start: 2011-06-30End: 2013-02-28Updated: 2020-12-19
Effect of LIK066 on Glucose Absorption in Patients With Type 2 Diabetes Mellitus
CompletedNCT01915849
Start: 2013-07-31End: 2014-01-31Updated: 2015-02-06
Phase 2
Dose-finding Study of LIK066 Compared With Placebo or Sitagliptin to Evaluate Change in HbA1c in Patients With Diabetes
WithdrawnNCT01824264
Start: 2015-11-30End: 2016-11-30Updated: 2014-04-03
Effect of LIK066 on Body Weight in Patients With Elevated Body Mass Index
CompletedNCT02470403
Start: 2015-06-05End: 2016-04-04Updated: 2021-01-05
A Study to Evaluate the Change in Weight After 24 Weeks Treatment With LIK066 in Obese or Overweight Adults
CompletedNCT03100058
Start: 2017-05-06End: 2018-08-02Updated: 2020-02-06
Study of PK/PD, Safety and Tolerability of LIK066 in Patients With Decreased Renal Function.
CompletedNCT03131479
Start: 2017-04-28End: 2018-01-16Updated: 2021-01-05
A Dose Finding Study to Assess the Effect of LIK066 Compared to Placebo or Empagliflozin in Patients With Type 2 Diabetes Mellitus and Heart Failure
TerminatedNCT03152552
Start: 2017-07-25End: 2018-06-06Updated: 2019-08-28
Study of Pharmacodynamics of LIK066 in Overweight and Obese Women With Polycystic Ovary Syndrome
CompletedNCT03152591
Start: 2017-07-24End: 2018-06-25Updated: 2021-01-05
Effects of Carbohydrate in Diet and Supplements on the Gastrointestinal Tolerability of LIK066
CompletedNCT03198767
Start: 2017-06-21End: 2017-09-04Updated: 2021-01-05
Effect of LIK066 on Reduction of Fatty Content in Livers of Obese Patients
CompletedNCT03205150
Start: 2017-10-04End: 2019-11-14Updated: 2021-10-08
A Dose-finding Study to Evaluate the Change in Weight After Treatment With LIK066 in Japanese Patients With Obesity
CompletedNCT03320941
Start: 2017-12-07End: 2018-07-25Updated: 2024-06-26