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Lifitegrast 5% Ophthalmic Solution

DRUG8 trials

Sponsors

Weill Medical College of Cornell University, AbbVie, Bucci Laser Vision Institute, Eye Surgeons of Indiana, Research Insight LLC

Conditions

Dry EyeDry Eye DiseaseDry Eye SyndromeDry Eye SyndromesDry Eyes ChronicGraft-versus-host-diseaseOcular Graft-versus-host Disease

Early Phase 1

The Effects and Safety of 5% Lifitegrast Ophthalmic Solution in Subjects With Dry Eye Disease in Ocular Graft-versus-Host Disease
CompletedNCT04792580
Richard W Yee, MDGraft-versus-host-disease, Ocular Graft-versus-host Disease
Start: 2022-10-22End: 2024-04-30Updated: 2024-07-15

Phase 1

A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye Disease
CompletedNCT04030962
AbbVieDry Eye Disease, Dry Eye Syndrome
Start: 2020-03-04End: 2022-03-18Updated: 2025-05-20

Phase 2

A Research Study To See How Well an Eye Drop, SURF-100 (A Mycophenolic Acid/Betamethasone Sodium Phosphate Combination), Works and What Side Effects There Are in Subjects With Dry Eye Disease
CompletedNCT04734197
Surface Ophthalmics, Inc.Dry Eye Disease
Start: 2021-01-11End: 2022-03-25Updated: 2025-05-11

Phase 4

Effect of Lifitegrast 5% on Tear Film Markers
WithdrawnNCT03952481
Weill Medical College of Cornell UniversityDry Eye, Dry Eyes Chronic, Dry Eye Syndromes
Start: 2021-03-01End: 2021-12-31Updated: 2021-02-16
Ocular Inflammation in Cataract Patients and Response to Treatment With Xiidra
WithdrawnNCT04120987
Bucci Laser Vision InstituteDry Eye
Start: 2021-05-31End: 2022-06-25Updated: 2023-07-27
Xiidra vs. Xiidra + Dextenza Treatment for Dry Eye Disease
TerminatedNCT04413253
Eye Surgeons of IndianaDry Eye Syndromes
Start: 2020-08-01End: 2022-04-11Updated: 2022-04-18
The Chronology of Lifitegrast Effect on Anterior Surface Rehabilitation (CLEAR) Study
CompletedNCT04669561
Research Insight LLCDry Eye
Start: 2021-03-17End: 2021-10-08Updated: 2021-10-12
Lifitegrast 5% for the Treatment of Dry Eye In Habitual Soft Contact Lens Wearers
CompletedNCT05505292
State University of New York College of OptometryDry Eye
Start: 2022-09-22End: 2023-05-15Updated: 2025-01-14

Related Papers

Selecting Vehicle Comparators in Dry Eye Disease Clinical Trials: Implications for Efficacy and Safety Assessment and Regulatory Outcomes.
2026-09-07
Effects and Safety of 5% Lifitegrast Ophthalmic Solution in Patients With Dry Eye Disease Associated With Ocular Graft-Versus-Host Disease.
2024-08-08