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LGG

DRUG6 trials

Sponsors

Turku University Hospital, Washington University School of Medicine, Chr Hansen, Prince of Songkla University, Eskisehir Osmangazi University

Conditions

Acute Infectious Diarrhoea in ChildrenBreastfeedingFunctional Abdominal Pain SyndromeGastroenteritisGastrointestinal NeoplasmsHealthy Response to ProbioticsPremature; Infant, Light-for-dates

Phase 1

Probiotic LGG for Prevention of Side Effects in Patients Undergoing Chemoradiation for Gastrointestinal Cancer
TerminatedNCT01790035
Washington University School of MedicineGastrointestinal Neoplasms
Start: 2014-08-19End: 2021-12-12Updated: 2022-03-16

Phase 2

Impact of Emergency Department Probiotic (LGG) Treatment of Pediatric Gastroenteritis
CompletedNCT01773967
Washington University School of MedicineGastroenteritis
Start: 2014-07-31End: 2018-08-31Updated: 2019-09-06

Phase 4

The Effects of Probiotics, Lactobacillus GG, in the Treatment of Abdominal Pain in Children With Functional Abdominal Pain Disorders
RecruitingNCT06310733
Prince of Songkla UniversityFunctional Abdominal Pain Syndrome
Start: 2024-03-21End: 2026-02-20Target: 54Updated: 2024-03-18

Unknown Phase

Probiotics and Early Microbial Contact in Preterm Neonates
NCT01454661
Turku University HospitalBreastfeeding, Premature; Infant, Light-for-dates
Start: 2014-04-30End: 2019-04-30Target: 100Updated: 2018-04-19
Defining the Normal Human Response to Probiotics
CompletedNCT03140878
Chr HansenHealthy Response to Probiotics
Start: 2017-04-16End: 2017-06-11Updated: 2018-04-23
Evaluating the LGG of on Acute Infectious Diarrhea in Children
Not yet recruitingNCT07342101
Eskisehir Osmangazi UniversityAcute Infectious Diarrhoea in Children
Start: 2026-01-01End: 2027-12-31Target: 480Updated: 2026-01-15

Related Papers

Pathogen-Specific Effects of Probiotics in Children With Acute Gastroenteritis Seeking Emergency Care: A Randomized Trial
Clinical Infectious Diseases2021-09-3017 citations
Variables Associated With Intravenous Rehydration and Hospitalization in Children With Acute Gastroenteritis
JAMA Network Open2021-04-197 citations
Personalized B cell response to the <i>Lactobacillus rhamnosus GG</i> probiotic in healthy human subjects: a randomized trial
Gut Microbes2020-11-0916 citations
Association between Age, Weight, and Dose and Clinical Response to Probiotics in Children with Acute Gastroenteritis
Journal of Nutrition2020-09-188 citations
<i>Lactobacillus rhamnosus</i> GG versus Placebo for Acute Gastroenteritis in Children
New England Journal of Medicine2018-11-21190 citations
<i>Lactobacillus rhamnosus</i>GG protects the intestinal epithelium from radiation injury through release of lipoteichoic acid, macrophage activation and the migration of mesenchymal stem cells
Gut2018-06-22206 citations
Randomised controlled trial of <i>Lactobacillus rhamnosus</i> (LGG) versus placebo in children presenting to the emergency department with acute gastroenteritis: the PECARN probiotic study protocol
BMJ Open2017-09-2419 citations
Impact of emergency department probiotic treatment of pediatric gastroenteritis: study protocol for the PROGUT (Probiotic Regimen for Outpatient Gastroenteritis Utility of Treatment) randomized controlled trial.
2014-05-1420 citations