Levoketoconazole

DRUG5 trials

Sponsors

Cortendo AB

Conditions

Cushing DiseaseCushing SyndromeEndogenous Cushing's SyndromeHealthyHealthy Subjects

Phase 1

Levoketoconazole Food Effect Study in Healthy Subjects

CompletedNCT03768388

Cortendo ABHealthy Subjects

Start: 2018-11-30End: 2018-12-24Updated: 2019-02-04

Bioavailability of Levoketoconazole and Ketoconazole Tablets

CompletedNCT04212000

Cortendo ABHealthy

Start: 2019-12-16End: 2020-01-23Updated: 2020-01-31

Phase 3

Treatment for Endogenous Cushing's Syndrome

CompletedNCT01838551

Cortendo ABEndogenous Cushing's Syndrome

Start: 2014-08-31End: 2018-11-30Updated: 2021-04-19

A Study to Assess the Safety and Efficacy of Levoketoconazole in the Treatment of Endogenous Cushing's Syndrome.

CompletedNCT03277690

Cortendo ABEndogenous Cushing's Syndrome

Start: 2017-09-26End: 2020-08-31Updated: 2022-11-08

Open-label Treatment in Cushing's Syndrome

CompletedNCT03621280

Cortendo ABCushing Disease, Cushing Syndrome

Start: 2019-01-07End: 2022-12-31Updated: 2025-06-19

Related Papers

Levoketoconazole in the Treatment of Patients With Cushing’s Syndrome and Diabetes Mellitus: Results From the SONICS Phase 3 Study

Frontiers in Endocrinology2021-04-0727 citations

Levoketoconazole improves clinical signs and symptoms and patient-reported outcomes in patients with Cushing’s syndrome

Pituitary2020-11-2023 citations

MON-332 Safety and Efficacy of Levoketoconazole in the Treatment of Endogenous Cushing’s Syndrome (LOGICS): A Double-Blind, Placebo-Controlled, Withdrawal Study

Journal of the Endocrine Society2020-04-013 citations

Efficacy and safety of levoketoconazole in the treatment of endogenous Cushing's syndrome (SONICS): a phase 3, multicentre, open-label, single-arm trial.

2019-09-1874 citations