Leucovorin (LV)

DRUG9 trials

Conditions

Carcinoma, Non-Small-Cell LungColorectal CancerColorectal NeoplasmsGC/GEJCGastroesophageal Junction AdenocarcinomaKRAS P.G12CMetastatic Pancreatic CancerPancreatic Cancer

Phase 1

A Dose Escalation Study of MM-398 Plus Irinotecan in Patients With Unresectable Advanced Cancer

CompletedNCT02640365

GERCOR - Multidisciplinary Oncology Cooperative GroupUnresectable Advanced Cancer

Start: 2015-11-18End: 2016-12-07Updated: 2017-01-31

Study of Sotorasib Combined With Chemotherapy for Second Line Treatment of Pancreas Cancer

WithdrawnNCT05251038

Devalingam MahalingamKRAS P.G12C, Metastatic Pancreatic Cancer, Pancreatic Cancer +1

Start: 2022-09-13End: 2023-01-31Updated: 2023-05-11

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

RecruitingNCT06131840

Seagen, a wholly owned subsidiary of PfizerCarcinoma, Non-Small-Cell Lung, Colorectal Neoplasms, Gastroesophageal Junction Adenocarcinoma +3

Start: 2023-11-20End: 2030-09-12Target: 914Updated: 2026-03-13

Newly Emerging Immunotherapy for Pancreatic Cancer Treatment

Not yet recruitingNCT06370754

Fudan UniversityPancreatic Cancer

Start: 2024-04-30End: 2027-04-30Target: 117Updated: 2024-04-17

Phase 2

Study of Enzastaurin With 5-Fluorouracil/Leucovorin (5-FU/LV) Plus Bevacizumab as Maintenance Regimen Following First Line Therapy for Metastatic Colon Cancer

CompletedNCT00612586

Eli Lilly and CompanyColorectal Cancer

Start: 2008-02-29End: 2011-11-30Updated: 2020-07-21

Study of Gamma Interfereon in Metastatic Colorectal Carcinoma

CompletedNCT00786643

Accelerated Community Oncology Research NetworkColorectal Cancer

Start: 2006-02-28End: 2010-03-31Updated: 2012-03-01

Colorectal Cancer RECHALLENGE

WithdrawnNCT00988897

SanofiColorectal Neoplasms

Start: 2009-10-31End: 2012-05-31Updated: 2009-12-23

Mecapegfilgrastim Combined With Adebrelimab and Chemotherapy as Neoadjuvant Therapy in Resectable GC/GEJC

Not yet recruitingNCT06684158

The First Affiliated Hospital with Nanjing Medical UniversityGC/GEJC

Start: 2024-11-30End: 2027-12-01Target: 70Updated: 2024-11-12

Phase 3

A Study of Xeloda (Capecitabine) Plus Oxaliplatin in Patients With Colon Cancer

CompletedNCT00069121

Hoffmann-La RocheColorectal Cancer

Start: 2003-04-18End: 2011-04-21Updated: 2020-03-06

Related Papers

An open-label phase 1 study to investigate SGNCEACAM5C/SAR445953 in adults with advanced solid tumors (SGNCEA5C-001).

Journal of Clinical Oncology2024-06-013 citations

Abstract CT077: An open-label phase 1 study to investigate SGN-CEACAM5C in adults with advanced solid tumors (SGNCEA5C-001, Trial in Progress)

Cancer Research2024-04-05

Abstract 2118: SGN-CEACAM5C/SAR445953, a novel topoisomerase I inhibitor antibody-drug conjugate targeting CEACAM5, has potent anti-tumor activity in CRC, PDAC, GC and lung cancer tumor models

Cancer Research2024-03-22