Letrozole tablets

DRUG17 trials

Sponsors

Queen Mary Hospital, Hong Kong, Tolmar Inc., Cairo University, Zagazig University, Ente Ospedaliero Ospedali Galliera

Conditions

Advanced Breast CancerAdvanced Unresectable or Metastatic Breast Cancer of AdultsAnembryonic PregnancyBreast CancerCarcinoma, Ovarian EpithelialEctopic PregnancyGestational Trophoblastic DiseaseInfertility, Male

Phase 1

Phase I Study of BEBT-209 in Women With Advanced Breast Cancer

BeBetter Med IncAdvanced Breast Cancer

Start: 2019-07-15End: 2023-11-20Target: 106Updated: 2023-09-21

Letrozole Alone Protocol Versus Using Letrozole and HCG Protocol

CompletedNCT06367712

EgymedicalpediaPCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Start: 2022-11-10End: 2023-11-10Updated: 2024-04-16

A Clinical Study of HRS-6209 Combined With Other Treatment Regimens in Patients With Breast Cancer

RecruitingNCT06974929

Jiangsu HengRui Medicine Co., Ltd.Breast Cancer

Start: 2025-05-22End: 2025-12-31Target: 80Updated: 2025-12-30

A Study of HRS-6208 in Combination With HRS-8080, or Fulvestrant, or Letrozole, With or Without HRS-6209 in Patients With Advanced Unresectable or Metastatic Breast Cancer

RecruitingNCT07389733

Shandong Suncadia Medicine Co., Ltd.Advanced Unresectable or Metastatic Breast Cancer of Adults

Start: 2026-03-27End: 2028-12-01Target: 180Updated: 2026-04-03

Phase 2

Letrozole as a Prophylaxis From GTN for Complete Mole Patients

Zagazig UniversityGestational Trophoblastic Disease

Start: 2020-06-01End: 2023-06-01Updated: 2022-07-12

Impact of Co Enzyme Q10 as Adjuvant Therapy to Letrozole on Spermiogram

CompletedNCT05847257

Al-Mustansiriyah UniversityInfertility, Male, Male Reproductive Problem

Start: 2021-12-01End: 2022-10-30Updated: 2025-02-19

Phase 3

Letrozole in Tubal Ectopic Pregnancy

Queen Mary Hospital, Hong KongTubal Pregnancy

Start: 2020-12-01End: 2025-03-31Target: 214Updated: 2023-04-10

Ovarian Suppression Evaluating Subcutaneous Leuprolide Acetate in Breast Cancer

Active, not recruitingNCT04906395

Tolmar Inc.Breast Cancer

Start: 2021-07-01End: 2026-04-30Target: 250Updated: 2026-01-13

Letrozole for Estrogen/Progesterone Receptor Positive Low-grade Serous Epithelial Ovarian Cancer (LEPRE Trial)

RecruitingNCT05601700

Ente Ospedaliero Ospedali GallieraCarcinoma, Ovarian Epithelial, Low Grade Serous Adenocarcinoma of Ovary

Start: 2022-09-22End: 2029-09-22Target: 132Updated: 2025-01-27

Safety Extension Study for Subjects With HR+, HER2- Breast Cancer for Subjects Who Have Completed the OVELIA Study

Enrolling by invitationNCT05645536

Tolmar Inc.Breast Cancer

Start: 2022-12-28End: 2028-06-30Target: 250Updated: 2026-01-12

A Phase 3 Study of HRS-8080 Versus Treatment Chosen by Physicians in Locally Advanced and Metastatic Breast Cancer

RecruitingNCT07024173

Shandong Suncadia Medicine Co., Ltd.Locally Advanced Breast Cancer, Metastatic Breast Cancer

Start: 2025-07-23End: 2027-12-01Target: 240Updated: 2026-01-26

A Phase III Trial Comparing HRS-8080 With Standard Endocrine Therapy in Patients With High-Risk Early Breast Cancer

RecruitingNCT07349069

Shandong Suncadia Medicine Co., Ltd.Breast Cancer

Start: 2026-03-04End: 2034-01-01Target: 4800Updated: 2026-03-19

Phase 4

Evaluation of Different Doses of Letrozole in Ectopic Pregnancy

CompletedNCT05198141

Zagazig UniversityEctopic Pregnancy

Start: 2020-12-15End: 2022-01-01Updated: 2022-01-20

Use of Letrozole for Ectopic Pregnancy

RecruitingNCT06354439

Hospital de Clinicas de Porto AlegreEctopic Pregnancy

Start: 2024-03-27End: 2026-12-31Target: 130Updated: 2024-04-09

Unknown Phase

Letrozole in Induction of Abortion of Anembryonic Pregnancy

CompletedNCT05198050

Cairo UniversityAnembryonic Pregnancy

Start: 2022-04-03End: 2022-09-30Updated: 2023-09-11

Laboratory and Ultrasound Findings and Response to Letrozole in PCOS Patients

Not yet recruitingNCT06861803

Al-Azhar UniversityPCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Start: 2025-04-01End: 2025-12-30Target: 138Updated: 2025-03-21

Letrozole and Cabergoline Versus Letrozole Alone in Ovulation Induction

CompletedNCT07168837

Al-Azhar UniversityPCOS (Polycystic Ovary Syndrome)

Start: 2023-01-10End: 2024-05-10Updated: 2025-09-11

Related Papers

Letrozole for hormone receptor-positive low-grade ovarian cancer: Preliminary toxicity results of a phase III trial.

2025-12-14

Abstract OT3-04-01: A Phase 3 study evaluating ovarian suppression following three-month leuprolide acetate in combination with endocrine therapy in premenopausal subjects with HR+, HER2-negative breast cancer (OVELIA)

Cancer Research2023-03-01

Impact of coenzyme Q10 as an adjuvant therapy to letrozole on spermiogram results and sex hormone levels in Iraqi men with infertility; randomized open label comparative study.

2023-01-012 citations

A phase 3, single arm, open-label study evaluating ovarian suppression following 3-month leuprolide acetate for injectable suspension in combination with endocrine therapy in premenopausal subjects with HR+, HER2-negative breast cancer (OVELIA).

Journal of Clinical Oncology2022-06-011 citations