Lentiviral vector transduced CD34+ cells

DRUG2 trials

Sponsors

Great Ormond Street Hospital for Children NHS Foundation Trust

Conditions

P47-Phox, Deficiency ofSevere Combined Immunodeficiency, X-Linked

Phase 1

Lentiviral Gene Therapy for X-linked Severe Combined Immunodeficiency

RecruitingNCT03601286

Great Ormond Street Hospital for Children NHS Foundation TrustSevere Combined Immunodeficiency, X-Linked

Start: 2018-12-21End: 2026-08-31Target: 5Updated: 2023-10-12

Lentiviral Gene Therapy for p47 AR-CGD

RecruitingNCT05207657

Great Ormond Street Hospital for Children NHS Foundation TrustP47-Phox, Deficiency of

Start: 2023-03-20End: 2029-04-01Target: 5Updated: 2023-05-16

Related Papers

Lentiviral Gene Therapy with Low Dose Conditioning for X-Linked SCID Results in Complete Immune Reconstitution and No Evidence of Clonal Expansion

Blood2022-11-152 citations